SYBR GREEN I Nucleic Acid Gel Stain Cas: 163795-75-3 99% Yolimba
| Nambala ya Catalog | XD90236 |
| Dzina lazogulitsa | SYBR GREEN I Nucleic Acid Gel Stain |
| CAS | 163795-75-3 |
| Molecular Formula | Chithunzi cha C32H37N4S |
| Kulemera kwa Maselo | 509.728 |
| Zambiri Zosungira | -20 ° C |
Mafotokozedwe a Zamalonda
| Maonekedwe | White ufa |
| Kuyesa | 99% |
Flow cytometry ndi njira yopangira ma in vitro antimalarial sensitivity assay ndi kuthekera kochulukira kogwiritsidwa ntchito m'malo akumunda.Tinafufuza za kutengeka kwa mankhwala asanu ndi awiri oletsa malungo a 40 atsopano a P. falciparum omwe amadzipatula kudzera mu njira ya flow cytometry (FCM), mtundu wa LDH-based ELISA: DELI), ndi kusanthula kwazithunzi kakang'ono ka kukula.Kwa FCM, zoyeserera za 184/280 (66%) zidakwaniritsa njira zovomerezera, poyerekeza ndi 166/280 (59%) ya DELI.Panali mgwirizano wabwino pakati pa FCM ndi microscopy, pomwe DELI inkakonda kupanga zoletsa zoletsa zoletsa kwambiri (IC50s) kuposa FCM, ndi kukondera kwa 2.2-fold (kuyerekeza kwa Bland-Altman).Makhalidwe a artesunate ndi dihydroartemisinin adakhudzidwa kwambiri.Kuwonjezeka kodabwitsa kwa ma siginecha pamilingo yayikulu kwambiri ya mefloquine ndi zinthu zina zofananira zidadziwika kwambiri ndi kuyesa kwa DELI, kuwonetsa kuti zotsatira zoyipa zomwe zingachitike pakupanga LDH zitha kukhala ndi udindo.Kutayika kwa chizindikiro cha FCM chifukwa cha kubwereranso kapena kukula pang'onopang'ono kunawonedwa mu zitsanzo zochepa.Zotsatirazi zimakulitsa ntchito yapitayi yogwiritsira ntchito cytometry yothamanga kuti mudziwe kuti muli ndi vuto la antimalarial malinga ndi chiwerengero cha zitsanzo, mankhwala osiyanasiyana, ndi kuyerekezera ndi njira zina.
