Zogulitsa

Kuti tidziwe zambiri za kusintha kwa mast cell mu khungu lodziwika bwino komanso lodwala, njira yatsopano ya enzyme-histochemical yodetsa pawiri ndi katatu idagwiritsidwa ntchito yomwe imalola kuzindikira kwa metachromasia (toluidine blue) ndi mast cell proteases tryptase ndi chymase mkati mwa thupi. cell yomweyo.Zigawo za Cryostat zidagwiritsidwa ntchito pakhungu kuchokera ku zitsanzo zotsatirazi: khungu labwinobwino (N = 4), psoriasis (N = 13), atopic eczema (N = 7), lichen planus (N = 6), interferon alpha 2a jekeseni (N = 13), = 1) a leukemic kulowa ndi lolingana yachibadwa khungu la wodwala yemweyo pamaso ndi pambuyo mankhwala.(i) Ziwerengero zofanana za tryptase- ndi chymase-positive mast cell (MCTC) zinapezedwa m'zitsanzo zonse zabwinobwino komanso za matenda mu papillary ndi reticular dermis, ndikuwonjezeka katatu kuzungulira zolumikizira.(ii) Maselo a tryptase-positive mast (MCT) analibe pakhungu labwinobwino, koma adawonjezedwa modabwitsa m'matenda okhudzana ndi matenda mkati mwa papillary dermis, infiltrate yotupa ndi zozungulira.(iii) Kuwonjezeka kwakukulu kwa MCT kunadziwikanso pa malo a jekeseni wa interferon mkati mwa leukemic infiltrate, koma osati pakhungu lachibadwa la wodwala yemweyo.Deta iyi ikuwonetsa kuti mphamvu za mast cell zomwe zimadalira matenda zimangokhala ndi MCT mu kutupa kwapakhungu komanso kuti manambala a MCT amawongoleredwa ndi zinthu zapadera, zokhudzana ndi matenda am'deralo.