Zogulitsa

Ma biofilms amapangidwa ndi ma cell a bakiteriya omwe amatsekeredwa munjira yodzipangira yokha, ya extracellular polymeric matrix.Poly-beta (1,6) -N-acetyl-d-glucosamine (PNAG) ndi gawo lalikulu la biofilm matrix mu mabakiteriya osiyanasiyana a phylogenetically.Mu phunziro ili tinafufuza zakuthupi ndi mankhwala a PNAG matrix mu biofilms opangidwa mu vitro ndi gram-negative porcine kupuma pathogen Actinobacillus pleuropneumoniae ndi gram-positive chipangizo chogwirizana ndi tizilombo toyambitsa matenda Staphylococcus epidermidis.Zotsatira za PNAG pakuyenda kwamadzimadzi ambiri zidadziwika poyesa kuchuluka kwa madzimadzi kudzera m'ma biofilms opangidwa muzosefera za centrifugal.Mlingo wa convection wamadzimadzi unali wokwera kwambiri mu biofilms wotukuka pamaso pa PNAG-owononga enzyme dispersin B kuposa ma biofilms opangidwa popanda enzyme, kuwonetsa kuti PNAG imachepetsa kutuluka kwamadzi ambiri.PNAG idatsekerezanso mayendedwe a quaternary ammonium compound cetylpyridinium chloride (CPC) kudzera mu biofilms.Kumanga kwa CPC ku biofilms kumalepheretsa kusuntha kwamadzimadzi ndikutsekereza mayendedwe a utoto wa azo Allura wofiira.Bioactive CPC idachotsedwa bwino kuchokera ku biofilms pothandizidwa ndi 1 M sodium chloride.Kuphatikizidwa pamodzi, zotsatirazi zikusonyeza kuti CPC imagwira ntchito mwachindunji ndi PNAG matrix ndikusintha mawonekedwe ake akuthupi ndi mankhwala.Zotsatira zathu zikuwonetsa kuti PNAG imakhala ndi gawo lofunikira pakuwongolera momwe thupi limagwirira ntchito ndipo lingathandizire kuzinthu zina zokhudzana ndi biofilm monga kukana kwa biocide.