Zogulitsa

Kugwiritsiridwa ntchito kwa silika capillary yopanda kanthu mu CE nthawi zina kumakhala kovutirapo chifukwa cha zotsatira zosafunikira kuphatikiza kutsatsa kwa zitsanzo kapena kusakhazikika kwa EOF.Izi nthawi zambiri zimatha kupewedwa ndikuphimba mkati mwa capillary.Mu ntchitoyi, timapereka ndikuwonetsa zokutira ziwiri za polyelectrolyte (PECs) poly(2-(methacryloyloxy)ethyl trimethylammonium iodide) (PMOTAI) ndi poly(3-methyl-1-(4-vinylbenzyl)-imidazolium chloride) (PIL- 1) kwa CE.Ma capillaries okutidwa adaphunziridwa pogwiritsa ntchito mabakiteriya amadzi a pH osiyanasiyana, mphamvu ya ma ionic, ndi kapangidwe kake.Zotsatira zathu zikuwonetsa kuti ma polyelectrolytes omwe amafufuzidwa amatha kugwiritsidwa ntchito ngati zokutira zokhazikika (zowoneka mwakuthupi) zokhala ndi kukhazikika kosachepera kasanu musanayambe kukonzanso kwakanthawi kochepa kofunikira.Ma PEC onsewa adawonetsa kukhazikika kwatsika kwambiri pa pH 11.0.EOF inali yokwera pogwiritsa ntchito mabafa a Good kuposa okhala ndi sodium phosphate buffer pa pH yomweyo ndi mphamvu ya ionic.Makulidwe a magawo a PEC omwe amawerengedwa ndi quartz cry stal microbalance anali 0.83 ndi 0.52 nm kwa PMOTAI ndi PIL-1, motsatana.Kuchuluka kwa hydrophobicity kwa zigawo za PEC kudatsimikiziridwa ndi kusanthula kwamitundu yosiyanasiyana ya ma alkyl benzoates ndikuwonetseredwa ngati magawo ogawa.Chotsatira chathu chimasonyeza kuti ma PEC onse anali ndi hydrophobicity yofanana, yomwe inachititsa kulekanitsa kwa mankhwala ndi log Po / w > 2. Kukhoza kusiyanitsa mankhwala a cationic kunasonyezedwa ndi β-blockers, mankhwala omwe nthawi zambiri amagwiritsidwa ntchito molakwika mu doping.Zovala zonsezi zinathanso kulekanitsa zinthu za hydrolysis za madzi a ionic 1,5-diazabicyclo [4.3.0] non-5-ene acetate pazikhalidwe za acidic kwambiri, pomwe ma capillaries osakanikirana a silica analephera kukwaniritsa kulekana.