Zogulitsa

The stromal microenvironment imayang'anira mammary gland branching morphogenesis.Tawona kuti ma cell cell amapezeka mu gland ya mammary panthawi yonse yomwe akubadwa ndipo, makamaka, amapezeka mozungulira ma terminal end buds ndi ductal epithelium ya pubertal gland.Maselo a mast amathandizira kuti ziwengo, matenda otupa, komanso kukula kwa khansa koma sizinaphatikizidwe ndikukula bwino.Kusokonezeka kwa ma genetic ndi pharmacological of mast cell function mu mammary gland kunawonetsa kuti ma mast cell amatenga nawo gawo pakuchulukirachulukira komanso kuphatikizika kwa ma ducts panthawi yakutha msinkhu, ndipo izi sizimayenderana ndi kulembedwa kwa ma macrophage, zomwe zimayang'aniranso kukula kwa gland ya mammary.Kuti maselo a mlongoti agwiritse ntchito zotsatira zake pa morphogenesis yachibadwa amafunika kutsegula ma serine proteases ndi degranulation.Zomwe taziwona zikuwonetsa gawo lachilendo la ma mast cell pakukula kwabwinobwino kwa mawere a mammary.