Zogulitsa

Chiwopsezo cha matenda a Staphylococcus aureus osamva methicillin omwe amatengedwa ndi anthu chikukwera kwambiri.Chithandizo chogwira mtima chakhala chikukhudza kale kuchotsedwa koyambirira komanso kupereka maantibayotiki.Kafukufukuyu adapangidwa kuti adziwe momwe chithandizo chamankhwala chimagwirira ntchito pochiza matenda a m'manja.Kuyesa kosasinthika komwe kunachitika kunachitika pachipatala cha Level I County.Odwala pamanja analandira empiric intravenous vancomycin atalandira kapena mtsempha wa cefazolin.Zotsatira zinatsatiridwa pogwiritsa ntchito kuopsa kwa matenda, kuyankhidwa koyenera kwachipatala, ndi kutalika kwa kukhala.Mtengo wamtengo wapatali unawerengedwa pogwiritsa ntchito ndalama zonse kwa wodwala aliyense m'magulu onse awiri.Kusanthula kwachiwerengero kunachitika. Odwala makumi anayi ndi asanu ndi limodzi adalembedwa mu phunziroli.Makumi awiri ndi anayi anali randomized kuti cefazolin (52.2 peresenti) ndi 22 (47,8 peresenti) kuti vancomycin.Panalibe kusiyana kwa chiwerengero pakati pa mtengo wa mankhwala (p <0.20) kapena kutalika kwa nthawi yokhala (p <0.18) pakati pa magulu.Odwala randomized kuti cefazolin anali apamwamba zikutanthauza mtengo wa mankhwala poyerekeza ndi odwala randomized kuti vancomycin (p <0,05).Odwala omwe ali ndi matenda oopsa kwambiri anali ndi mtengo wokwera mtengo wamankhwala (p <0.0001) komanso kutalika kwa nthawi yayitali (p = 0.0002).Kumapeto kwa kafukufukuyu, chiwerengero cha anthu omwe amapeza methicillin-resistant S. aureus pachipatala cha olemba mabuku chinapezeka kuti ndi 72 peresenti, zomwe zinachititsa kuti kafukufukuyu athetsedwe msanga ndi bungwe loyang'anira mabungwe chifukwa cha zochitika zambiri. Kusatengera zina mwachisawawa.Kuchiza koyenera koyambirira kwa methicillin-resistant S. aureus sikunatsimikizidwe motsimikizika.Palibe kusiyana kwa zotsatira zogwiritsira ntchito cefazolin motsutsana ndi vancomycin monga wothandizira woyamba adadziwika.