Zogulitsa

Vancomycin hydrochloride ndi mankhwala a glycopeptide ndipo ndi mchere wa hydrochloride wa vancomycin.Ndi woyera kapena woyera ngati crystalline ufa pa firiji.Limagwirira ake zochita ndi kuti akhoza kumanga ndi mkulu kuyanjana kwa poly-terminus alanyl-alanine wa kalambulabwalo peptide ili pa selo khoma tcheru bakiteriya maselo, kutsekereza biosynthesis wa peptide glycan polima kupanga bakiteriya selo khoma, motero. kumabweretsa kuwonongeka kwa khoma la cell ndikuphanso mabakiteriya.Komanso, n'zothekanso kusintha permeability wa bakiteriya selo nembanemba, ndi kusankha ziletsa synthesis wa RNA.Makhalidwe a vancomycin hydrochloride ndi mphamvu yake yowononga bactericidal motsutsana ndi mabakiteriya a Gram-positive monga Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, ndi streptococcus pneumoniae.Imakhalanso ndi zotsatira zotsutsana ndi mabakiteriya pa Streptococci anaerobius, Clostridium difficile, Bacillus anthracis, Actinomycetes, Corynebacterium diphtheria, Neisseria gonorrhoeae, Streptococcus viridans, Streptococcus bovis, ndi Streptococcus faecalis.Komabe, mabakiteriya ambiri a Gram-negative, Mycobacterium, Rickettsia genus, Chlamydia kapena bowa, ndizosavomerezeka.Imagwiritsidwa ntchito pochiza matenda omwe amayambitsidwa ndi Staphylococcus aureus osamva methicillin ndi mabakiteriya ena: sepsis, endocarditis, osteomyelitis, nyamakazi, kuvulala kwamoto, kuvulala kwapang'onopang'ono ndi matenda ena ongowoneka achiwiri, chibayo, abscess yamapapo, empyema, peritonitis, meningitis, pseudomembranous colitis, komanso matenda a pakhungu ndi minofu yofewa.Ndilo chisankho chachikulu kwa odwala omwe sali osagwirizana ndi penicillin ndipo akudwala enterococcal endocarditis ndi Corynebacterium (class diphtheria sp) endocarditis.