Streptavidin kuchokera ku Streptomyces avidinii CAS:9013-20-1
| Nambala ya Catalog | XD90329 |
| Dzina lazogulitsa | Streptavidin kuchokera ku Streptomyces avidinii |
| CAS | 9013-20-1 |
| Molecular Formula | Chithunzi cha C14H17BrClNO2S |
| Kulemera kwa Maselo | 378.71 |
| Zambiri Zosungira | -15 mpaka -20 ° C |
| Harmonize Tariff Code | 35040090 |
Mafotokozedwe a Zamalonda
| Maonekedwe | White ufa |
| Kuyesa | 99% |
| Zogwiritsidwa ntchito pofufuza zokha, osati za anthu | ntchito zofufuza zokha, osati za anthu |
Alkyne-hinged 3-fluorosialyl fluoride (DFSA) yomwe ili ndi gulu la alkyne idawonetsedwa kuti ndi chandamale chokhazikika cha sialidase inhibitor.Ester-protected analog DFSA (PDFSA) ndi kalambulabwalo wa membrane-permeable wa DFSA wopangidwa kuti azigwiritsidwa ntchito m'maselo amoyo, ndipo adawonetsedwa kuti akupanga covalent adducts ndi virus, bacteria, and human sialidases.The fluorosialyl-enzyme adduct imatha kulumikizidwa ndi azide-annexed biotin kudzera pamachitidwe ophatikizika ndikuzindikiridwa ndi ma signature a streptavidin-enieni.Liquid chromatography-mass spectrometry/mass spectrometry kusanthula pazidutswa za tryptic peptide kukuwonetsa kuti 3-fluorosialyl moiety imasintha zotsalira za tyrosine za sialidase.DFSA idagwiritsidwa ntchito kuwonetsa matenda a chimfine komanso kuzindikirika kwa kutengeka kwa ma virus ku anti-fluenza drug oseltamivir acid, pomwe PDFSA idagwiritsidwa ntchito pazithunzithunzi za kusintha kwa sialidase m'maselo amoyo.
