Zogulitsa

S-(+)-Methyl-(2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride, yomwe imadziwikanso kuti S-(+)-Clopidogrel, ndi mankhwala okhala ndi mankhwala a C16H16ClNO2S·HCl Ndi chochokera ku chiral cha clopidogrel, chomwe ndi mankhwala ofunika kwambiri oletsa kutsitsa magazi. Imakhala ndi zotsatira zake zochizira poletsa kuphatikizika kwa mapulateleti, kuletsa mapangidwe a magazi, komanso kuchepetsa chiopsezo cha zochitika zamtima ndi mitsempha yamagazi. Pomanga mosasinthika ku cholandilira ichi, S-(+)-Methyl-(2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride imalepheretsa kutsegulidwa kwa mapulateleti ndikuletsa mapangidwe. Kachitidwe kameneka kamapangitsa kukhala mankhwala ofunikira popewera matenda a thrombotic kwa odwala omwe ali pachiwopsezo chachikulu, monga omwe ali ndi mbiri ya acute coronary syndrome, ischemic stroke, kapena peripheral artery disease.S-(+) -Methyl- (2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride nthawi zambiri amaperekedwa pakamwa ngati mapiritsi kapena makapisozi.Pambuyo pakumwa, imasintha kagayidwe kachakudya m'chiwindi kuti ipange metabolite yake yogwira.Metabolite yogwira iyi imamangiriza mosasinthika ku cholandilira cha P2Y12, kutulutsa zotsatira zake za antiplatelet kwa nthawi yayitali.Mankhwalawa amaperekedwa kamodzi patsiku, ngati chithandizo chodziyimira payekha kapena kuphatikiza mankhwala ena a antiplatelet, monga aspirin. -thienyl)amino] acetate hydrochloride iyenera kugwiritsidwa ntchito motsogozedwa ndi akatswiri azachipatala, chifukwa kugwiritsidwa ntchito kwake kungakhale ndi kuthekera.