Rapamycin kuchokera ku Streptomyces hygroscopicus CAS: 53123-88-9 Yoyera mpaka yoyera kapena yachikasu crystalline ufa
| Nambala ya Catalog | XD90356 |
| Dzina lazogulitsa | Rapamycin kuchokera ku Streptomyces hygroscopicus |
| CAS | 53123-88-9 |
| Molecular Formula | C51H79NO13 |
| Kulemera kwa Maselo | 914.17 |
| Zambiri Zosungira | -20 ° C |
| Harmonize Tariff Code | 2942000000 |
Mafotokozedwe a Zamalonda
| Kuyesa | 99% |
| Maonekedwe | Choyera mpaka choyera kapena chachikasu cha crystalline ufa |
Rapamycin, mankhwala omwe awonetsedwa kuti akuwonjezera moyo wa mbewa, amalepheretsa njira ya rapamycin (TOR), njira yaikulu yomwe imayang'anira kukula kwa maselo ndi mphamvu.Aganiziridwa kuti rapamycin ndi restriction dietary (DR) amakulitsa moyo kudzera m'njira / njira zofanana.Pogwiritsa ntchito kusanthula kwa ma microarray, tidafanizira zolemba za minofu yoyera ya adipose kuchokera ku mbewa zodyetsedwa ndi rapamycin kapena chakudya cha DR kwa miyezi 6.Kusanthula kwamitundu yambiri komanso kuwunika kwa mapu otentha kunawonetsa kuti rapamycin inalibe mphamvu pa transcriptome poyerekeza ndi DR.Mwachitsanzo, zolemba zisanu ndi chimodzi zokha zidasinthidwa kwambiri ndi rapamycin pomwe mbewa zodyetsedwa ndi DR zidawonetsa kusintha kwakukulu pazolemba za 1000.Pogwiritsa ntchito kusanthula kwanzeru, tidapeza kuti stearate biosynthesis ndi circadian rhythm signing zidasinthidwa kwambiri ndi DR.Zomwe tapeza zikuwonetsa kuti DR, koma osati rapamycin, imakhudza kulembedwa kwa minofu ya adipose, kutanthauza kuti njira ziwirizi zimawonjezera moyo kudzera m'njira / njira zosiyanasiyana.
