N- Acetyl -L-cysteine CAS: 616-91-1 98% White crystalline ufa
| Nambala ya Catalog | XD90127 |
| Dzina lazogulitsa | N-Acetyl-L-cysteine |
| CAS | 616-91-1 |
| Molecular Formula | Chithunzi cha C5H9NO3S |
| Kulemera kwa Maselo | 163.1949 |
| Zambiri Zosungira | 2 mpaka 8 ° C |
| Harmonize Tariff Code | 29309016 |
Mafotokozedwe a Zamalonda
| Melting Point | 106-112 ° C |
| Kuzungulira kwachindunji | + 21 ° - + 25 ° |
| Zitsulo zolemera | <10ppm |
| Arsenic | <1ppm |
| pH | 2.0-2.8 |
| Kutaya pa Kuyanika | kuposa 1.0% |
| Sulfate | <0.03% |
| Kuyesa | 98% mphindi |
| Chitsulo | <20ppm |
| Zotsalira pa Ignition | .5% |
| Ammonium | <0.02% |
| cl | <0.04% |
| Maonekedwe | White crystalline ufa |
| State of Solution | > 98% |
N-Acetyl-L-cysteine ndi acetylated amino acid yokhala ndi antioxidant ndi mucolytic properties.Zochita ziwirizi zawonetsa kuti N-Acetyl-L-cysteine ndi yofunikira kwambiri pamankhwala a cystic fibrosis, pomwe antioxidant/kuchepetsa mawonekedwe a pawiri amathandizira mawonekedwe a systemic redox kusalinganika kwa CF ndi mucolytic katundu wa pawiri amalepheretsa kuchulukana ndi kutupa kumagwirizana ndi redox iyi.Monga mucolytic, N-Acetyl-L-cysteine imathandizira kuchotsa zomangira za disulfide kudutsa mucoproteins, kumasula ndikuchotsa kukhuthala kwa sputum.N-Acetyl-L-cysteine amawonetsa kuchitapo kanthu kwa glutathione, onse akuwonetsa zochita za antioxidant kudzera mu magwiridwe antchito a thiol, ndipo onse amawonetsedwa kuti amateteza kupsinjika kwa peroxidative komwe kumakhudzana ndi kugwedezeka kwa septic.N-Acetyl-L-cysteine yawonetsedwanso kuti imapangitsa apoptosis m'maselo osalala a mitsempha, zomwe zimasonyeza kuti maselowa amayankha mosiyana ndi kusintha kwa kuchepetsa-oxidation state kusiyana ndi minofu ina yomwe nthawi zambiri imatetezedwa ndi kukhalapo kwa antioxidants.Kulumikizana kodabwitsa kumeneku m'maselo osalala a minofu kukuwonetsa kuti N-Acetyl-L-cysteine ndi njira yodalirika yopititsira patsogolo kufalikira kwa ma cell awa.
Chemical katundu: N-acetyl-L-cysteine white crystalline ufa, ndi fungo ngati adyo ndi wowawasa kukoma.Hygroscopic, sungunuka m'madzi kapena ethanol, osasungunuka mu ether ndi chloroform.Ndi acidic mu njira yamadzimadzi (pH2-2.75 mu 10g/LH2O), mp101-107℃Chemicalbook.Izi ndizochokera ku N-acetylated kuchokera ku cysteine.Molekyu ili ndi gulu la sulfhydryl, lomwe limatha kuswa mgwirizano wa disulfide (-SS-) wa chomangira cha mucin peptide, potero kutembenuza unyolo wa mucin kukhala unyolo waung'ono wa peptide, kuchepetsa Chifukwa cha kukhuthala kwa mucin, mankhwalawa amasungunuka. mankhwala kwa viscous sputum, purulent sputum ndi kupuma ntchofu.
Kuyanjana kwamankhwala:
1. Osagwiritsidwa ntchito limodzi ndi maantibayotiki a penicillin, cephalosporin ndi tetracycline, chifukwa omalizawa amatha kukhala osagwira ntchito.
2. Kuphatikiza kapena kugwiritsa ntchito isoproterenol kumathandizira kuchiritsa komanso kuchepetsa zotsatira zoyipa.
3. Pewani kukhudzana ndi zitsulo ndi mphira ziwiya, okosijeni, ndi mpweya.
Ntchito: zopangira zamoyo, zopangira, thiol (-SH) mu molekyulu zimatha kuswa unyolo wa disulfide (-SS) wolumikiza unyolo wa mucin peptide mu mucous phlegm.Mucin amatembenuza Chemicalbook kukhala kachingwe kakang'ono ka peptide, komwe kumachepetsa kukhuthala kwa sputum;imathanso kuthyola ulusi wa DNA mu purulent sputum, kotero sichitha kusungunula sputum yoyera komanso purulent sputum.
Ntchito: Mankhwala, amagwiritsidwa ntchito ngati mankhwala osungunula phlegm.Pa kafukufuku wam'chilengedwe, amagwiritsidwa ntchito ngati mankhwala osungunula phlegm ndi poizoni wa acetaminophen muzamankhwala.
Ntchito: Pa kafukufuku wam'chilengedwe, mu zamankhwala, amagwiritsidwa ntchito ngati mankhwala osungunula phlegm komanso mankhwala ophera poizoni acetaminophen.
Ntchito: Zamoyo reagents, mankhwala, mankhwala ntchito ngati expectorant, amene amati n'zosavuta kuyeretsa phlegm ndi yosavuta kutsokomola.Zimakhala ndi kuwonongeka kwa viscous sputum.Njira yochitirapo kanthu ndi yakuti gulu la sulfhydryl lomwe lili mu maselo a mankhwalawa likhoza kuthyola mgwirizano wa disulfide Chemicalbook mu mucin polypeptide unyolo mu mucous sputum, kuwola mucin, kuchepetsa kukhuthala kwa sputum, ndikupangitsa kuti ikhale yamadzimadzi komanso yosavuta khosomola.Ndi oyenera pachimake ndi aakulu kupuma matenda ndi wandiweyani sputum ndi zovuta expectorate, komanso zizindikiro zovuta kuyamwa chifukwa chotsekereza kuchuluka kwa phlegm yomata.
Ntchito: N-acetyl-L-cysteine angagwiritsidwe ntchito ngati phlegm-kusungunuka mankhwala.Ndi oyenera kupuma kutsekeka chifukwa cha kuchuluka kwa zomata phlegm kutsekeka.Kuphatikiza apo, itha kugwiritsidwanso ntchito pochotsa poizoni wa acetaminophen.Chifukwa mankhwalawa ali ndi fungo lapadera, kutenga izo mosavuta kuchititsa nseru ndi kusanza.Zimakhala zolimbikitsa pa kupuma thirakiti ndipo zingayambitse bronchospasm.Amagwiritsidwa ntchito limodzi ndi bronchodilators monga isoproterenol ndi chipangizo chokoka sputum kuti atulutse sputum.Sitiyenera kukhudzana ndi zitsulo (monga Fe, Cu), mphira, okosijeni, etc. Sitiyenera kugwiritsidwa ntchito pamodzi ndi maantibayotiki monga penicillin, cephalosporin, tetracycline, etc., kuti asachepetse antibacterial effect.Gwiritsani ntchito mosamala odwala omwe ali ndi mphumu ya bronchial.
