Metronidazole Cas: 443-48-1
| Nambala ya Catalog | XD91888 |
| Dzina lazogulitsa | Metronidazole |
| CAS | 443-48-1 |
| Fomu ya Molecularla | Chithunzi cha C6H9N3O3 |
| Kulemera kwa Maselo | 171.15 |
| Zambiri Zosungira | 2-8 ° C |
| Harmonize Tariff Code | 29332990 |
Mafotokozedwe a Zamalonda
| Maonekedwe | White crystalline ufa |
| Asay | 99% mphindi |
| Malo osungunuka | 159-161 °C (kuyatsa) |
| Malo otentha | 301.12 ° C (kuyerekeza molakwika) |
| kachulukidwe | 1.3994 (kuyerekeza movutikira) |
| refractive index | 1.5800 (chiyerekezo) |
| Fp | 9 ℃ |
| kusungunuka | acetic acid: 0.1 M, yowoneka bwino, yachikasu pang'ono |
| pka | pKa 2.62(H2O,t =25±0.2,Iundefined) (Sizikudziwika) |
| Kusungunuka kwamadzi | <0.1 g/100 mL pa 20 ºC |
Metronidazole ndi mankhwala kusankha amebiases, nyini trichomonasis ndi trichomonadic urethritis amuna, lambliosis, amebic kamwazi, ndi matenda anaerobic chifukwa cha tizilombo tcheru mankhwala.Mafananidwe a mankhwalawa ndi flagyl, protostat, trichopol, ndi vagimid.
Metronidazole amapezeka m'kamwa, intravaginal, apakhungu, ndi parenteral kukonzekera.Amapangidwa ndi makampani angapo, koma amapezeka ndi mankhwala.Kuwonetseredwa mwangozi zachilengedwe sikungatheke, ndipo ngati zichitika, ndizokayikitsa kuti zingayambitse poizoni.
Amagwiritsidwa ntchito ngati antibacterial pochiza rosacea.Antiprotozoal (trichomonas).Carcinogen yotheka yamunthu.
Metronidazole ndi antiprotozoal ndi antibacterial agents.Amagwiritsidwa ntchito kwambiri pochiza kapena kupewa matenda am'deralo kapena am'deralo omwe amayamba chifukwa cha mabakiteriya a anaerobic, monga matenda a bakiteriya a anaerobic m'mimba, m'mimba, m'mimba, njira yoberekera ya mkazi, thirakiti la kupuma, khungu ndi zofewa, mafupa ndi mafupa, etc. , matenda a meningeal, ndi colitis chifukwa chogwiritsa ntchito maantibayotiki ndi othandizanso.Kafumbata nthawi zambiri amathandizidwa ndi kafumbata antitoxin (TAT).Angagwiritsidwenso ntchito m`kamwa anaerobic matenda.Pa Okutobala 27, 2017, mndandanda wazinthu zoyambitsa khansa zofalitsidwa ndi World Health Organisation's International Agency for Research on Cancer zidasanjidwa koyambirira kuti zigwiritsidwe ntchito, ndipo metronidazole idaphatikizidwa pamndandanda wamagulu a 2B a khansa.Mu Januwale 2020, metronidazole idasankhidwa kukhala gulu lachiwiri la mndandanda wazinthu zogulira mankhwala.
Metronidazole ndi wothandizira kwambiri omwe alipo pochiza anthu omwe ali ndi mitundu yonse ya amebiasis, mwina kupatulapo munthu yemwe alibe zizindikiro koma akupitiriza kutulutsa cysts.Izi zimafuna mankhwala a intraluminal amebicide, monga diloxanide furoate, paromomycin sulfate, kapena diiodohydroxyquin.Metronidazole yogwira motsutsana matumbo ndi extraintestinal cysts ndi trophozoites.
Ngakhale quinacrine hydrochloride wakhala ntchito zochizira giardiasis, madokotala ambiri amakonda metronidazole.Furazolidone ndi njira ina.
Metronidazole ndi mankhwala kusankha mu Europe kwa matenda bakiteriya anaerobic;nkhawa yokhudzana ndi kuthekera kwa carcinogenicity yapangitsa kuti pakhale chenjezo pakugwiritsa ntchito kwake ku United States.Posachedwapa zapezeka kuti ndizothandiza pochiza matenda a D. medinensis (Guinea worm) ndi Helicobacter pylori.
Amagwiritsidwanso ntchito pa acne rosacea, balantidiasis ndi matenda a Guinea worm.T. vaginalis matenda kugonjetsedwa ndi mwachizolowezi mlingo amafuna chithandizo chapadera.
