Methyl 1,2,3,4-tetra-O-acetyl-BD-glucuronate Cas: 7355-18-2 98%
Nambala ya Catalog | XD90029 |
Dzina lazogulitsa | methyl 1,2,3,4-tetra-O-acetyl-BD-glucuronate |
CAS | 7355-18-2 |
Molecular Formula | C15H20O11 |
Kulemera kwa Maselo | 376.31 |
Zambiri Zosungira | 2-8 ° C |
Harmonize Tariff Code | 29389090 |
Mafotokozedwe a Zamalonda
Maonekedwe | White mpaka pafupifupi ufa woyera mpaka kristalo |
Kuyesa | 98% |
Methyl 1,2,3,4-tetra-O-acetyl-β-D-glucuronate yakhala ikugwiritsidwa ntchito mu kafukufuku wofufuza mapangidwe ndi kaphatikizidwe ka madzi osungunuka a glucuronide ochokera ku camptothecin kwa khansa prodrμg monotherapy ndi antibody-directed enzyme prodrμg. chithandizo.Zagwiritsidwanso ntchito pofufuza kuti afufuze kaphatikizidwe ndi gawo la glycosylthio heterocycles mu carbohydrate chemistry.
Kuphatikizika kwa zotumphukira za pentopyranic acid
N4-Benzoylcytosine 1-(methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate) yapezeka ndi zokolola za 70% ndi glycosylation ya trimethylsilyl yochokera ku N4-benzoylcytosine ndi methyl 1,2 ,3,4-tetra-O-acetyl-β-D-glucopyranuronate pamaso pa atatu ofanana ndi SnCl4 monga condensing agent.Cytosine 1-(β-D-glucopyranosiduronamide) (IV) - amide wa pentopyranic acid - yapangidwa mwazokolola zochulukirapo ndi ammonolysis ya nucleoside (I).