Lipase kuchokera ku nkhumba za nkhumba CAS: 9001-62-1 Brown mpaka beige ufa
| Nambala ya Catalog | XD90387 |
| Dzina lazogulitsa | Lipase kuchokera ku nkhumba za nkhumba |
| CAS | 9001-62-1 |
| Molecular Formula | N / A |
| Kulemera kwa Maselo | N / A |
| Zambiri Zosungira | 2 mpaka 8 ° C |
| Harmonize Tariff Code | 35079090 |
Mafotokozedwe a Zamalonda
| Phulusa | <12% |
| AS | <2mg/kg |
| Pb | <2mg/kg |
| M'madzi | <8% |
| Kuyesa | 99% |
| Ntchito ya enzyme | >30000u/g |
| Maonekedwe | Brown mpaka beige ufa |
| Gulu la Coliform | <30MPH/100g |
| Zogwiritsidwa ntchito pofufuza zokha, osati za anthu | ntchito zofufuza zokha, osati za anthu |
Kusintha kwa kagayidwe ka triglyceride (TG) m'maselo a vascular smooth muscle (SMC) kuyenera kukhala kogwirizana ndi mtundu wina wa phenotype, ngakhale izi sizinadziwike.Adipose triglyceride lipase (ATGL) imagwira ntchito yayikulu ya TG m'maselo adipotic ndi omwe si adipotic.Mu kafukufuku wapano, tidapatula SMC ku ATGL-deficie mbewa (ATGL(-/-)mSMC).ATGL(-/-)mSMC inawonetsa kudzikundikira kwa TG modzidzimutsa ndi kuyankha kochepa kwa mitogenic ndi mawu osalala a minofu actin (SMA) poyerekeza ndi ATGL (+/+) mSMC.Maperesenti a maselo abwino a _-galactosidase okhudzana ndi senescence adawonjezekanso mu ATGL (-/-) mSMC.PCR yanthawi yeniyeni yotsatiridwa ndikuwunika ndi kuwunika koyang'ana kwa DNA komwe kunavumbulutsa mawu okhazikika a glucokinase (1.7-fold), lipoprotein lipase (3.8-fold) ndi interleukin-6 (3.7-fold) ndikuwonetsa kutsika kwamphamvu kwa mitsempha yomaliza. factor-A (0.2-fold), type I collagen (0.5-fold), and transforming growth factor-_ (0.4-fold) mu ATGL(-/-) mSMC poyerekeza ndi ATGL(+/+)mSMC.Kenako, ectopic gene transfer of human ATGL anayesera kugwiritsa ntchito doxycycline (Dox) -regulatable myc-DDK-tagged adenovirus vector (AdvATGL).Matenda a AdvATGL adachepetsa kuchuluka kwa TG ndi kuyankha kokwezeka kwa mitogenic ndi mawu a SMA, komanso kuchepa kwa ma cell a senescent mu ATGL (-/-) mSMC.Kuphatikiza apo, mawonekedwe amtundu wopatuka mu ATGL(-/-)mSMC adakonzedwanso.Deta yathu imasonyeza kuti ATGL (-/-) mSMC ili ndi phenotype yosiyana yomwe ingakhale yokhudzana ndi mitsempha ya mitsempha.Plasticity ya SMC phenotypes yolumikizidwa ndi lipid metabolism ikhoza kukhala chandamale chachipatala.
