L-Histidine Cas: 71-00-1 98.5% Makristasi oyera kapena ufa wa crystalline
| Nambala ya Catalog | XD90301 |
| Dzina lazogulitsa | L-Histidine |
| CAS | 71-00-1 |
| Molecular Formula | C6H9N3O2 |
| Kulemera kwa Maselo | 155.15 |
| Zambiri Zosungira | Wozungulira |
| Harmonize Tariff Code | 29332990 |
Mafotokozedwe a Zamalonda
| Kuyesa | 98.5% mphindi |
| Maonekedwe | Makristasi oyera kapena ufa wa crystalline |
| Gulu | USP39 |
| Kuzungulira kwachindunji | +12.6 ° mpaka +14.0 ° |
| Chizindikiritso | Mayamwidwe a infrared |
| pH | 7.0 - 8.5 |
| SO4 | <= 0.03% |
| Fe | <=30ppm |
| Kutaya pa Kuyanika | <=0.2% |
| Zotsalira pa Ignition | <=0.1% |
| Cl | <= 0.05% |
| Zitsulo zolemera (PB) | <=15ppm |
| Zogwirizana nazo | Osapitirira 0.5% ya zonyansa zilizonse zomwe zimapezeka;Osapitirira 2.0% ya zonyansa zonse zomwe zimapezeka |
he quadruplex kupanga mndandanda wa G-rich amagawidwa mosiyanasiyana mumtundu wa munthu.Kulemera kwawo mu olimbikitsa oncogenic ndi ma telomeres kwadzetsa chidwi choloza G-quadruplex (GQ) pamankhwala oletsa khansa.Apa, tikuwonetsa kusanthula kwachulukidwe pakusintha ndi kusinthika kwa ma GQ kupanga ma mayendedwe oyesedwa ndi fulorosisi imodzi ya molekyulu.Kuphatikiza apo, timagwirizanitsa zinthuzi ndi GQ yolunjika ma ligands ndi kumanga mapuloteni a G4 resolvase 1 (G4R1).Chotsatira chathu chikuwonetsa kuti zonse zozungulira (zigawo zomwe sizili za G) kutalika ndi kutsatizana zimathandizira kuti GQ ikhale yogwirizana.Kufufuza kwa nthawi yeniyeni ya molekyulu imodzi kumawonetsa kuti kupindika kwamphamvu kumadaliranso kapangidwe ka lupu.Tikuwonetsa kuti GQ-kukhazikika kwa mamolekyu ang'onoang'ono, N-methyl mesoporphyrin IX (NMM), analogi yake, NMP ndi mapuloteni a G4R1 amamanga mosankha ku GQ conformation.Zomwe tapeza zimaloza kuzovuta kwa kupukutira kwa GQ motsogozedwa ndi kutalika kwa loop ndi kutsatizana kwake komanso momwe kulumikizana kwa GQ kumazindikirira kamolekyu kakang'ono ndi kaphatikizidwe ka mapuloteni.
