Zogulitsa

7-Hydroxygranisetron ndi mankhwala omwe amagwira ntchito ngati mankhwala.Ndi m'gulu la mankhwala omwe amadziwika kuti selective serotonin 5-HT3 receptor antagonists.Pagululi ndi metabolite ya granisetron, mankhwala omwe amagwiritsidwa ntchito kwambiri.Cholinga chachikulu cha 7-Hydroxygranisetron ndi kuteteza ndi kuchiza nseru ndi kusanza, makamaka zomwe zimagwirizanitsidwa ndi chemotherapy kapena opaleshoni.Zotsatira zoyipazi zimatha kusokoneza moyo wa wodwala ndipo zingayambitse kusokonezeka kwa chithandizo.7-Hydroxygranisetron imagwira ntchito poletsa zolandilira za serotonin m'katikati mwa mitsempha, makamaka zomwe zili mu chemoreceptor trigger zone ndi malo osanza.Pochita zimenezi, zimathandiza kuchepetsa zizindikiro zomwe zimayambitsa nseru ndi kusanza, kupereka mpumulo kwa odwala.Kuphatikiza pa ntchito yake ya CINV, 7-Hydroxygranisetron yasonyezanso kulonjeza poyang'anira nseru ndi kusanza pambuyo pa opaleshoni (PONV).Pambuyo pa opaleshoni, odwala nthawi zambiri amakhala ndi nseru ndi kusanza chifukwa cha zotsatira za anesthesia ndi zina.7-Hydroxygranisetron imathandiza kupewa ndi kulamulira zizindikirozi, kulola odwala kuti achire bwino.Akagwiritsidwa ntchito, 7-Hydroxygranisetron nthawi zambiri amaperekedwa kudzera m'mitsempha kapena pamlomo, malingana ndi momwe wodwalayo alili komanso zofunikira zachipatala.Mlingo ukhoza kusiyanasiyana malinga ndi kulemera kwa munthu, njira yake kapena chithandizo chake, komanso kuopsa kwa zizindikiro.Ndikofunikira kutsatira mlingo woperekedwa ndi malangizo operekedwa ndi akatswiri a zaumoyo kuti atsimikizire kuti akugwira ntchito bwino komanso kupewa zotsatira zilizonse.Monga mankhwala ambiri, 7-Hydroxygranisetron ikhoza kukhala ndi zotsatirapo.Izi zingaphatikizepo mutu, kudzimbidwa, kutsegula m'mimba, chizungulire, ndi kutopa.Nthawi zina, anthu amatha kukumana ndi zovuta zina kapena zovuta zina.Ndikofunikira kufotokozera za zizindikiro kapena machitidwe kwa wothandizira zaumoyo kuti awonedwe moyenera ndi kasamalidwe.Pomaliza, 7-Hydroxygranisetron ndi mankhwala omwe amagwiritsidwa ntchito makamaka pofuna kupewa ndi kuchiza nseru ndi kusanza zomwe zimagwirizanitsidwa ndi chemotherapy ndi njira za opaleshoni.Poletsa ma serotonin receptors m'katikati mwa mitsempha, zimathandiza kuchepetsa zizindikiro zosautsa izi mwa odwala khansa komanso anthu omwe achira opaleshoni.Komabe, monga ndi mankhwala aliwonse, izo