Pamaso pa 2.8 mM D-shuga, beta-D-glucose pentaacetate (1. 7 mM) amawonjezera kutulutsidwa kwa insulin kuchokera kuzilumba zapang'onopang'ono za makoswe kuposa alpha-D-glucose pentaacetate.Momwemonso, kuwonjezereka kwina kwa insulin yotulutsidwa ndi nateglinide (0.01 mM) kunali kokulirapo pazisumbu zomwe zimakhala ndi beta osati alpha-D-glucose pentaacetate.Mosiyana ndi izi, pamaso pa 2.8 mM wosadziwika wa D-glucose, alpha-L-glucose pentaacetate, koma osati beta-L-glucose pentaacetate, amawonjezera kwambiri kutulutsa kwa insulin.Kuchuluka kwa insulinotropic potency ya beta-anomer ya D-glucose pentaacetate kunagwirizana ndi mfundo yakuti idakulitsa kwambiri chiŵerengero chowirikiza pakati pa D- [U-14C] glucose oxidation ndi D- [5-3H] kugwiritsa ntchito shuga, pamene alpha-D -glucose pentaacetate analephera kutero.Zomwe anapezazi zimatanthauziridwa kuti zigwirizane ndi lingaliro lakuti kukondoweza kwa insulini kutulutsidwa ndi ma esterwa makamaka kumabwera chifukwa cha kuyanjana kwawo mwachindunji ndi stereospecific receptor, ndi kukonda kasinthidwe ka C1 wamba kukhala beta-D-glucose pentaacetate ndi alpha-L- glucose pentaacetate.
