Zogulitsa

Kufufuza zotsatira za exogenous dextranase ndi sodium fluoride pa S. mutans monospecies biofilm.S.mutans 25175 idakula mu sing'anga ya soya ya tryptone, ndipo biofilm idapangidwa pazithunzi zamagalasi ndi 1.0% sucrose.Exogenous dextranase ndi sodium fluoride anawonjezeredwa yekha kapena palimodzi.Biofilm morphology idawunikidwa ndi confocal laser scanning microscopy.Zotsatira za mankhwalawa pa adhesion ndi exopolysaccharide kupanga ndi biofilms zinayesedwa ndi kuwerengera kwa scintillation ndi njira ya anthrone, motero. sodium fluoride mosiyana.Komabe, dextranase pamodzi ndi kuchepa kwa sodium fluoride kungathe kuwononga bwino mtengo wamtengo wapatali wa biofilm, ndipo kumapangitsa kuti mabakiteriya asamagwirizane kwambiri kuposa pamene dextranase kapena fluoride anagwiritsidwa ntchito okha (P <0.05).Kuchuluka kwa exopolysacchari de soluble and insoluble exopolysacchari de kunachepetsedwa kwambiri pophatikiza dextranase ndi sodium fluoride yochepa kwambiri, kuposa pamene anagwiritsidwa ntchito okha (P <0.05).Deta iyi imasonyeza kuti dextranase ndi kuchepa kwa sodium fluoride kungakhale ndi zotsatira za synergistic motsutsana ndi S. mutans biofilm ndikuwonetsa kugwiritsa ntchito mankhwala otsika kwambiri a sodium fluoride mu mankhwala a anticaries.