Zogulitsa

Clopidogrel camphorsulfonate ndi mankhwala opangidwa ndi mankhwala C16H16ClNO2S·C10H16O4S.Amadziwika kuti Clopidogrel S-oxide camphorsulfonate kapena Clopidogrel CAMS.Pagululi ndi chochokera ku chiral cha clopidogrel, chomwe ndi mankhwala omwe amagwiritsidwa ntchito kwambiri ndi antiplatelet. Kugwiritsa ntchito kwakukulu kwa Clopidogrel camphorsulfonate ndi gawo logwira ntchito popanga mankhwala a antiplatelet.Zimagwira ntchito poletsa kuphatikizika kwa mapulateleti, kuletsa mapangidwe a magazi, komanso kuchepetsa chiopsezo cha zochitika zamtima.Pulogalamuyi imayang'ana kwambiri cholandilira cha P2Y12 pamapulateleti, potero kutsekereza njira yotsegulira ndikuletsa kuphatikizika kwa mapulateleti.Limagwirira ntchito amapangitsa Clopidogrel camphorsulfonate ogwira popewera thrombosis ndi kuchepetsa zochitika za chokhwima mtima zochitika, kuphatikizapo matenda a mtima ndi sitiroko.Clopidogrel camphorsulfonate zambiri kutumikiridwa pakamwa mu mawonekedwe a mapiritsi kapena makapisozi.Akangolowetsedwa, amasintha kagayidwe kachakudya m'chiwindi, zomwe zimapangitsa kupanga metabolite yogwira.Metabolite yogwira iyi imamangiriza ku cholandilira cha P2Y12 mosasinthika, kutulutsa zotsatira zake za antiplatelet kwa nthawi yayitali.Pazachipatala, Clopidogrel camphorsulfonate nthawi zambiri amaperekedwa kwa odwala omwe ali ndi matenda oopsa, monga angina osakhazikika ndi infarction ya myocardial, kapena omwe adakumana ndi vuto la percutaneous coronary. intervention (PCI) ndi kuyika kokhazikika.Amagwiritsidwanso ntchito kwambiri pofuna kupewa kuchitika kwa thrombotic zochitika kwa odwala omwe ali ndi mbiri ya sitiroko kapena zotumphukira mtsempha wamagazi.Ndikofunikira kudziwa kuti Clopidogrel camphorsulfonate iyenera kugwiritsidwa ntchito moyang'aniridwa ndi dokotala, chifukwa imatha kuyanjana ndi mankhwala ena kapena kukhala ndi zotsutsana ndi zina. anthu odwala.Mlingo ndi nthawi ya chithandizo zimatha kusiyanasiyana malinga ndi momwe wodwalayo alili, ndipo kuwunika pafupipafupi kwa magazi ndi kuyezetsa magazi kungakhale kofunikira kuti muwonetsetse kuti achire ali ndi mphamvu zokwanira zochiritsira. makamaka omwe ali ndi arterial thrombosis.Ma antiplatelet ake komanso kuletsa kosankha kwa cholandilira cha P2Y12 kumapangitsa kuti ikhale mankhwala othandiza kuchepetsa chiopsezo cha zochitika zoyipa zamtima.Komabe, monga momwe zimakhalira ndi mankhwala aliwonse, kusamala kuyenera kuchitidwa pakugwiritsa ntchito kwake, ndipo odwala ayenera kutsatira malangizo ndi malangizo a dokotala.