Zogulitsa

Kuwerengetsera globulin (okwana mapuloteni - albumin) kawirikawiri anayesedwa ngati gawo la chiwindi ntchito mayeso mbiri mu chisamaliro chachikulu ndi sekondale ndipo amatsimikiza seramu globulin ndende, amene immunoglobulins ndi chigawo chachikulu.Kugwiritsa ntchito kwakukulu mpaka pano kwa globulin yowerengeka ndikuzindikira ma paraprotein pomwe mulingo uli wokwera.Kafukufukuyu adafufuza kuthekera kogwiritsa ntchito ma globulin owerengeka owerengeka kuti azindikire kuperewera kwa ma antibody.Zitsanzo za seramu yokhala ndi ma globulin owerengeka odulidwa <18 g/l kutengera zotsatira za kafukufuku woyendetsa ndege adasonkhanitsidwa kuchokera ku zipatala zisanu ndi zinayi ku Wales m'miyezi 12.Zambiri zopempha zosadziwika zidapezedwa ndipo zitsanzozo zidayesedwa kuti zikhale ndi milingo ya immunoglobulin, serum electrophoresis komanso, ngati kuli koyenera, immunofixation.Kuyerekeza njira yoyezera albumin pogwiritsa ntchito bromocresol yobiriwira ndi bromocresol yofiirira idapangidwa.Makumi asanu ndi atatu mphambu asanu ndi anayi pa 100 aliwonse (737 mwa 826) anali ndi immunoglobulin (Ig) G mlingo wochepera 6 g/l pogwiritsa ntchito njira yobiriwira ya bromocresol yokhala ndi f <18 g/l, ndipo 56% (459) anali nayo. IgG ndi <4 g/l.Odwala omwe ali ndi vuto lachiwiri komanso loyamba la antibody anapezeka ndipo serum electrophoresis ndi immunofixation anasonyeza kuti 1 · 2% (10) anali asanazindikire ma paraproteins ang'onoang'ono omwe amagwirizanitsidwa ndi immune-paresis.Pogwiritsa ntchito bromocresol yofiirira, 74% ya zitsanzo zinali ndi IgG yochepera 6 g/l pogwiritsa ntchito kudulidwa kwa <23 g/l.Kuwunika pogwiritsa ntchito ma globulin owerengeka omwe ali ndi mfundo zodulidwa zimazindikira kuperewera kwa ma antibody ndi ma paraprotein atsopano okhudzana ndi immune-paresis.Ndi yotchipa, yopezeka mofala komanso yosagwiritsidwa ntchito mokwanira.Odwala omwe alibe ma antibodies apezeka pogwiritsa ntchito zidziwitso zochokera ku ma globulin owerengeka, kufupikitsa kuchedwa kwa matenda komanso nthawi yolandira chithandizo ndi immunoglobulin m'malo mwa mankhwala.