Zogulitsa

8-Bromo-3-methyl-xanthine, yemwenso amadziwika kuti 8-BMX, ndi gulu lopanga la gulu la xanthines.Xanthines ndi gulu la mankhwala omwe amafanana ndi caffeine ndipo amakhala ndi zotsatira zofanana ndi thupi.Komabe, 8-BMX makamaka siigwiritsidwa ntchito kawirikawiri kapena yodziwika bwino poyerekeza ndi ma xanthines ena monga caffeine kapena theophylline.Imodzi mwa ntchito zazikulu za 8-BMX ili mu kafukufuku wa sayansi monga wotsutsana ndi adenosine receptors.Adenosine ndi mankhwala omwe amapezeka mwachibadwa m'thupi omwe amakhala ngati neuromodulator ndipo amagwira ntchito zosiyanasiyana za thupi, kuphatikizapo kugona, kutupa, ndi ntchito ya mtima.Poletsa ma adenosine receptors, 8-BMX ikhoza kusintha njirazi ndikupatsa ofufuza chidziwitso chamtengo wapatali pa ntchito ya adenosine mu machitidwe osiyanasiyana. dongosolo.Zagwiritsidwa ntchito pofufuza za nkhawa, kukhumudwa, ndi matenda a neurodegenerative monga Parkinson's ndi Alzheimer's.Poletsa ma adenosine receptors, 8-BMX imatha kusintha ma neurotransmission ndipo ingakhale ndi zotsatira zochiritsira m'mikhalidwe iyi.Komabe, ziyenera kuzindikiridwa kuti kugwiritsa ntchito 8-BMX m'maphunzirowa ndi kuyesa kwakukulu ndipo sikunamasuliridwe kukugwiritsidwa ntchito kwachipatala. .Mwachitsanzo, yakhala ikugwiritsidwa ntchito ngati chida chophunzirira ntchito ya adenosine receptors mu cardiorespiratory function ndi kufufuza zotsatira za adenosine receptor antagonists pamtima ndi mapapo.Kuonjezera apo, 8-BMX yafufuzidwa chifukwa cha kuthekera kwake pakusintha momwe chitetezo cha mthupi chimayankhira ndi kuchepetsa kutupa.Ndikofunikira kuzindikira kuti ngakhale 8-BMX yaphunziridwa kuti igwiritsidwe ntchito ndi zotsatira zake, ntchito zake zothandiza kunja kwa kafukufuku ndizochepa.Monga gulu lopangira, silipezeka pamalonda kuti ligwiritsidwe ntchito wamba kapena kumwa.M'makampani opanga mankhwala, ma xanthine ena monga caffeine kapena theophylline amagwiritsidwa ntchito kwambiri chifukwa cha mbiri yawo yachitetezo ndi zotsatira zodziwika bwino. mu kafukufuku wasayansi monga wotsutsa wosankha wa adenosine receptors.Zaphunziridwa chifukwa cha zotsatira zake pakatikati pa mitsempha ya mitsempha, ntchito ya mtima, ndi kutupa.Komabe, ntchito zake zogwira ntchito kunja kwa kafukufuku ndizochepa, ndipo ma xanthine ena monga caffeine amagwiritsidwa ntchito kwambiri komanso amadziwika.