Popitiliza kufunafuna mankhwala otetezeka komanso ogwira mtima a antidiabetic, algae am'madzi amakhala gwero lofunikira lomwe limapereka mankhwala angapo ochizira.Alpha-amylase, alpha-glucosidase inhibitors, ndi mankhwala ophera antioxidant amadziwika kuti athetse matenda a shuga ndipo alandira chidwi kwambiri posachedwapa.Mu phunziro lino, algae anayi obiriwira (Chaetomorpha aerea, Enteromorpha intestinalis, Chlorodesmis, ndi Cladophora rupestris) adasankhidwa kuti ayese alpha-amylase, alpha-glucosidase inhibitory, ndi antioxidant ntchito mu vitro. .Ntchito ya antidiabetic idawunikidwa ndi kuthekera koletsa kwa zotulutsa zotsutsana ndi alpha-amylase ndi alpha-glucosidase ndi ma spectrophotometric assays.Antioxidant ntchito anatsimikiza ndi 2,2-diphenyl-1-picrylhydrazyl, hydrogen peroxide (H2O2), ndi nitric okusayidi scavenging assay.Kusanthula kwa gasi chromatography-mass spectrometry (GC-MS) kunachitika kuti adziwe chigawo chachikulu chomwe chimayambitsa matenda a shuga. Pakati pa zotulutsa zosiyanasiyana zomwe zafufuzidwa, chloroform Tingafinye wa C. aerea (IC50 - 408.9 μg/ml) ndi methanol Tingafinye wa Chlorodesmis. (IC50 - 147.6 μg/ml) adawonetsa kuletsa kothandiza kwa alpha-amylase.Zomwe zatulutsidwazo zidawunikidwanso pakuletsa kwa alpha-glucosidase, ndipo palibe zochitika zomwe zidapezeka.Methanol Tingafinye wa C. rupestris anasonyeza odziwika ufulu kwakukulu scavenging ntchito (IC50 - 666.3 μg/ml), kenako H2O2 (34%) ndi nitric okusayidi (49%).Kuphatikiza apo, mbiri yamankhwala yopangidwa ndi GC-MS idawulula kukhalapo kwa mankhwala akuluakulu a bioactive.Phenol, 2,4-bis (1,1-dimethylethyl) ndi z, z-6,28-heptatriactontadien-2-imodzi amapezeka makamaka muzitsulo za methanol za C. rupestris ndi chloroform extract ya C. aerea.Zotsatira zathu zikuwonetsa kuti algae osankhidwa amawonetsa zoletsa za alpha-amylase ndi antioxidant ntchito.Choncho, maonekedwe a mankhwala omwe amagwira ntchito komanso zoyesa zake za vivo zidzakhala zochititsa chidwi. Algae wobiriwira anayi anasankhidwa kuti ayese alpha-amylase, alpha-glucosidase inhibitory, ndi antioxidant ntchito mu vitro C. aerea ndi Chlorodesmis anasonyeza kulepheretsa kwakukulu kwa alpha-amylase, ndi C. rupestris adawonetsa ntchito yodziwika bwino yothamangitsa mwachanguPalibe ntchito yomwe idawonedwa idapezeka motsutsana ndi alpha-glucosidaseGC-MS kusanthula kwa zotulutsa zogwira kumawulula kukhalapo kwa mankhwala akuluakulu omwe amapereka chidziwitso pa antidiabetic ndi antioxidant ntchito ya ndere izi.Mafupipafupi ogwiritsidwa ntchito: DPPH: 2,2-diphenyl-1-picrylhydrazyl, BHT: Butylated hydroxytoluene, GC-MS: Gas chromatography-mass spectrometry.
