Zogulitsa

2-(Chloromethyl) -4-methylquinazoline ndi mankhwala omwe ali a banja la quinazoline.Quinazolines ndi organic mankhwala okhala ndi bicyclic kapangidwe wopangidwa ndi mphete benzene wosakanikirana ndi pyrimidine mphete.Chigawo chapaderachi chimakhala ndi kuthekera kwakukulu kogwiritsidwa ntchito muzinthu zosiyanasiyana, kuphatikizapo mankhwala ndi sayansi ya zipangizo.Chigawo chimodzi chachikulu chomwe 2-(chloromethyl) -4-methylquinazoline yasonyeza lonjezo ili mu chemistry yamankhwala.Zotumphukira za Quinazoline zimakhala ndi zinthu zosiyanasiyana zachilengedwe, zomwe zimapangitsa kuti zikhale zokopa pakupezeka kwamankhwala ndi chitukuko.Aphunziridwa chifukwa cha kuthekera kwawo pochiza matenda osiyanasiyana, kuphatikizapo khansa, matenda a ubongo, ndi matenda a mtima.Mu kafukufuku wa khansa, mankhwala opangidwa ndi quinazoline awonetsa zotsatira zotsutsana ndi zotupa komanso zotsutsana ndi zotupa.Poletsa njira zinazake kapena mapuloteni omwe akukhudzidwa ndi kukula kwa maselo a khansa ndi kupulumuka, awonetsa kuthekera ngati othandizira othandizira.Kukhalapo kwa gulu la chloromethyl mu 2-(chloromethyl) -4-methylquinazoline kungapitirire kupititsa patsogolo mphamvu yake, monga momwe olowa m'malo a halogen asonyezedwa kuti apititse patsogolo bioactivity ndi kusankha kwa mankhwala. Ma enzymes omwe amakhudzidwa ndi matenda a neurodegenerative, monga Alzheimer's ndi Parkinson's.Mankhwalawa awonetsa kuti amatha kuwoloka chotchinga cha magazi-ubongo, kuwapangitsa kukhala okongola kwambiri poyang'ana dongosolo lapakati la mitsempha.Kupatulapo ntchito zawo zachipatala, quinazolines apezanso ntchito mu sayansi ya zinthu.Mapangidwe awo apadera a mamolekyu, kuphatikizidwa ndi kuthekera kwawo kosintha mitundu yosiyanasiyana yamankhwala, amawapangitsa kukhala midadada yosunthika yomangira zida zogwirira ntchito.Zidazi zimatha kuwonetsa zinthu monga fluorescence, electroconductivity, ndi kuzindikira kwa maselo, zomwe zimapangitsa kuti zikhale zothandiza m'madera monga optoelectronics, sensing, ndi catalysis. mapulogalamu.Zosiyanasiyana zamakina, monga kusinthana, kuphatikizika, ndi kulumikizana, zitha kugwiritsidwa ntchito kuyambitsa magulu ogwirira ntchito kapena kusintha kapangidwe kake.Kusinthasintha kumeneku kumapangitsa ochita kafukufuku kupanga ndi kupanga zowonjezera ndi zinthu zowonjezera kapena zogwira ntchito.Bioactivity yake, makamaka mu kafukufuku wa khansa ndi neuropharmacology, imapangitsa kuti ikhale yochititsa chidwi pakupanga mankhwala.Kuphatikiza apo, mawonekedwe ake osunthika amapangitsa kukhala chomangira chofunikira chazinthu zogwirira ntchito m'magawo osiyanasiyana.Pamene kafukufuku akupita patsogolo, kufufuza kwina kudzawulula kuthekera konse ndi kugwiritsidwa ntchito kwa gululi m'magawo osiyanasiyana a sayansi ndiukadaulo.