Bakiteriya wa entomopathogenic, Xenorhabdus nematophila, amachititsa kuti tizilombo towononga tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda polepheretsa ntchito ya phospholipase A(2) (PLA(2)).Posachedwapa, jini ya PLA (2) yokhudzana ndi chitetezo cha mthupi inadziwika kuchokera ku kachilomboka kofiira, Tribolium castaneum.Kafukufukuyu adapanga jini iyi ya PLA (2) mu vekitala yofotokozera mabakiteriya kuti apange enzyme yophatikizanso.The recombinant T. castaneum PLA (2) (TcPLA (2)) anasonyeza khalidwe enzyme ntchito ndi gawo lapansi ndende, pH, ndi yozungulira kutentha.Makhalidwe ake a biochemical amafanana ndi mtundu wachinsinsi wa PLA (2) (sPLA (2)) chifukwa ntchito yake inali yoletsedwa ndi dithiothreitol (ochepetsetsa wa disulfide bond) ndi bromophenacyl bromide (sPLA (2) inhibitor) koma osati ndi methylarachidonyl. fluorophosphonate (mtundu wina wa cytosolic wa PLA (2)).Msuzi wa chikhalidwe cha X. nematophila unali ndi PLA (2) inhibitory factor(s), yomwe inali yochuluka kwambiri muzofalitsa zomwe zinapezedwa panthawi ya kukula kwa bakiteriya.The PLA(2) inhibitory factor(s) inali yosagwira kutentha ndipo yotengedwa mu tizigawo tamadzi tamadzi ndi organic.Zotsatira za kagawo kakang'ono ka PLA (2) -inhibitory pa immunosuppression ya T. castaneum inali yofanana ndi yomwe imachokera ku kulepheretsa kwa TcPLA (2) kufotokozera jini ndi kusokoneza kwa RNA.
