Zogulitsa

Kufufuza kwa phytochemical kwa chomera chonse cha Lepisorus contortus (Christ) Ching kudapangitsa kuti adzipatula asanu atsopano a phenylethanoid glycosides (1-5), iliyonse ili ndi gulu la caffeoyl, flavonoid glycoside yatsopano (10), ndi 14 yodziwika bwino (6-9). ndi 11-15, syringic acid, vanillic acid, phloretic acid, diplopterol, ndi β-sitosterol).Ili ndilo lipoti loyamba la phenylethanoid glycosides kuchokera ku banja la Polypodiaceae.Ma Compounds 1-15 adawunikidwa chifukwa cha kuthekera kwawo kwa khansa ya chemopreventive potengera kuthekera kwawo koletsa chotupa cha necrosis factor alpha (TNF-α) -induced NF-κB ntchito, nitric oxide (NO) kupanga, ndi aromatase, quinone reductase 2 (QR-2) ), ndi ntchito za COX-1/-2.Quercetin-3-O-β-d-glucoside (15) inasonyeza kulepheretsa QR2 ndi IC (50) mtengo wa 3.84 μM, zomwe zinatsimikizira kaempferol / quercetin glycosides monga mankhwala ogwira ntchito kuti athetse QR2.Pulogalamuyi inasonyezanso ntchito ya NF-κB ndi mtengo wa IC (50) wa 33.6 μM.Kuonjezera apo, mankhwala 1, 2, 4, ndi 6 amasonyeza ntchito ya omatase ndi IC (50) mfundo za 30.7, 32.3, 26.8, ndi 35.3 μM, motero.