Tiamulin 98% Cas: 125-65-5
| Nambala ya Catalog | XD91893 |
| Dzina lazogulitsa | Tiamulin 98% |
| CAS | 125-65-5 |
| Fomu ya Molecularla | C22H34O5 |
| Kulemera kwa Maselo | 378.5 |
| Zambiri Zosungira | -20 ° C |
| Harmonize Tariff Code | 2918199090 |
Mafotokozedwe a Zamalonda
| Maonekedwe | White ufa |
| Asay | 99% mphindi |
| Malo osungunuka | 170-1710C |
| alpha | D24 +20° (c = 3 mu abs ethanol) |
| Malo otentha | 482.8±45.0 °C(Zonenedweratu) |
| kachulukidwe | 1.15±0.1 g/cm3(Zonenedweratu) |
| kusungunuka | DMSO:> 10mg/mL (kutentha) |
| pka | 12.91±0.10 (Zonenedweratu) |
| kuwala ntchito | [α]/D +30 mpaka +40° (c=1; CH2Cl2) |
Pleuromutilin ndi diterpene yopangidwa ndi mitundu ingapo ya basidomycete, makamaka Pleurotus, yomwe inapezeka mu 1951. za zochita.Pleuromutilin imalepheretsa kaphatikizidwe ka mapuloteni pomanga ku domain V ya 23S rRNA ndipo izi zapangitsa kuti pakhale ma analogue a semi-synthetic monga maantibayotiki a m'badwo watsopano, monga tiamulin ndi retapamulin.
Pleuromutilins monga tiamulin ndi valnemulin akhala akugwiritsidwa ntchito kwa nthawi yayitali mu mankhwala a Chowona Zanyama pochiza matenda a nkhumba.Posachedwapa mankhwala a semisynthetic pleuromutilin, retapamulin, adayambitsidwa ngati mankhwala apakhungu a matenda a Gram-positive mwa anthu.Pleuromutilins amalepheretsa ntchito ya peptidyl transferase ya bakiteriya 50S ribosomal subunit pomanga ku malo A.
