Tetracycline hydrochloride CAS: 64-75-5 99% Yellow crystalline ufa
| Nambala ya Catalog | XD90366 |
| Dzina lazogulitsa | Tetracycline hydrochloride |
| CAS | 64-75-5 |
| Molecular Formula | Chithunzi cha C22H24N2O8 |
| Kulemera kwa Maselo | 480.90 |
| Zambiri Zosungira | -15 mpaka -20 ° C |
| Harmonize Tariff Code | 29413000 |
Mafotokozedwe a Zamalonda
| Mapeto | Imagwirizana ndi BP2013, EP7, USP38 |
| Zitsulo zolemera | <0.005% |
| Chidetso Chimodzi | <0.1% |
| Chizindikiritso | IR, UV, HPLC, TLC |
| pH | 1.8-2.8 |
| Kutaya pa Kuyanika | <2.0% |
| Zosungunulira zotsalira | n-Butanol <3000ppm |
| Kuyesa | BP2013/EP7 99% |
| Phulusa la Sulfate | <0.5% |
| Kuzungulira kwapadera kwa kuwala | -240 mpaka -255 ° |
| Mphamvu | USP 38:> 900ug/mg |
| Zonse Zonyansa | <5% |
| Maonekedwe | Yellow crystalline ufa |
| 4-epianhydrotetracycline | <2% |
| Malire a tizilombo | Zimagwirizana |
| 4-Epiteracycline | <3% |
| Anhydrotetracyoline | <0.5% |
| Chlortetracycline Hydrochloride | <0.5% |
| Zosungunulira Zotsalira | <100ppm |
Kukula kwa kukana kwa antimicrobial kwapatsidwa mochulukira komanso kugwiritsa ntchito molakwika ma antimicrobial agents.Staphylococci ndi mbali ya zomera zachibadwa koma ndi tizilombo toyambitsa matenda tomwe tayamba kugonjetsedwa ndi maantibayotiki ambiri odziwika.Kukaniza mu coagulase negative staphylococci (CoNS) akuti kusinthika chifukwa cha kukakamizidwa kosankha kotsatira chithandizo cha maantibayotiki.Kafukufukuyu adafufuza kupezeka kwa ma antimicrobial agents asanu ndi anayi omwe amagwiritsidwa ntchito kwambiri mumkodzo wa anthu kuchokera kwa odwala kunja kwa zipatala ziwiri ku Ghana mogwirizana ndi kukana kwa CoNS.Mkodzo ndi CoNS zinayesedwa (n = 246 ndi n = 96 motsatira) kuchokera kwa odwala m'zipatala ziwiri ku Ghana.CoNS idadziwika pogwiritsa ntchito Gram staining, coagulase test, ndi MALDI-TOF/MS, ndipo kutengeka kwa antimicrobial ku 12 antimicrobial omwe amagwiritsidwa ntchito nthawi zambiri kumatsimikiziridwa ndi kufalikira kwa disk.Komanso njira yowunikira idapangidwa kuti adziwe zida zisanu ndi zinayi zomwe zimagwiritsidwa ntchito kwambiri ku Ghana pogwiritsa ntchito ma solid-ph ase m'zigawo pamodzi ndi HPLC-MS/MS pogwiritsa ntchito ionization ya electron spray.Wapamwamba pafupipafupi kukana kwa CoNS unachitika kwa penicillin V (98%), trimethoprim (67%), ndi tetracycline (63%).S. haemolyticus inali yodzipatula yodziwika bwino (75%), yotsatiridwa ndi S. epidermidis (13%) ndi S. hominis (6%).S. haemolyticus inalinso mitundu yomwe ikuwonetsa kufalikira kwamphamvu kwambiri (82%).69% ya CoNS yodzipatula inali yosamva mankhwala angapo (≧ 4 maantibayotiki) ndipo 45% ya CoNS inali yolimbana ndi methicillin.Ma antimicrobial agents adapezeka mu 64% ya zitsanzo za mkodzo (n = 121) pomwe mankhwala opha majeremusi omwe amapezeka pafupipafupi anali ciprofloxacin (30%), trimethoprim (27%), ndi metronidazole (17%).Zotsatira zazikulu za phunziroli zinali kuti kufalikira kwa mankhwala oletsa tizilombo toyambitsa matenda mumkodzo kunali mobwerezabwereza kusiyana ndi momwe odwala amagwiritsira ntchito odwala komanso kufalikira kwa S. haemolyticus yosagwirizana ndi mitundu ina ya CoNS yolimbana ndi tizilombo toyambitsa matenda pamene tizilombo toyambitsa matenda tinapezeka mu mkodzo.
