Tazobactam Cas: 89786-04-9
| Nambala ya Catalog | XD92373 |
| Dzina lazogulitsa | Tazobactam |
| CAS | 89786-04-9 |
| Fomu ya Molecularla | Chithunzi cha C10H12N4O5S |
| Kulemera kwa Maselo | 300.29 |
| Zambiri Zosungira | -15 mpaka -20 ° C |
| Harmonize Tariff Code | 29419000 |
Mafotokozedwe a Zamalonda
| Maonekedwe | Ufa woyera mpaka woyera |
| Asay | 99% mphindi |
| Madzi | <0.5% |
| Kuzungulira kwachindunji | + 127 mpaka +139 |
| Zitsulo zolemera | <20ppm |
| Zotsalira pa Ignition | <0.1% |
| Zonse Zonyansa | <1.0% |
Tazobactam ndi penicillanic acid sulfone yomwe imakhala yofanana ndi sulbactam.Ndi β-lactamaseinhibitor yamphamvu kuposa sulbactam ndipo imakhala ndi zochita zambiri pang'ono kuposa clavulanic acid.Lili ndi antibacterialactivity yofooka kwambiri.Tazobactam imapezeka mu mlingo wokhazikika, jekeseni wosakanikirana ndi piperacillin, penicillin yochuluka kwambiri yokhala ndi chiŵerengero cha 8: 1 cha piperacillin sodium ku tazobactamsodium ndi kulemera kwake ndikugulitsidwa pansi pa dzina la malonda Zosyn. Pharmacokinetics ya mankhwala awiriwa ndi ofanana kwambiri.Onsewa amakhala ndi moyo waufupi (t1/2 ~ 1 ora), amakhala ndi mapuloteni pang'ono, samadziwa kagayidwe kake, ndipo amatulutsidwa mumkodzo mochuluka kwambiri.
Zizindikiro zovomerezeka za piperacillin–tazobactamcombination zimaphatikizapo chithandizo cha appendicitis, postpartumendometritis, ndi matenda otupa m'chiuno oyambitsidwa ndi beta-lactamase-kupanga E. coli ndi Bacteroides spp., matenda a khungu ndi khungu omwe amayamba chifukwa cha β-lactamase-producingS.aureus, ndi chibayo choyambitsidwa ndi β-lactamase-producingstrains of H. influenzae.
