Streptomycin sulfate CAS:3810-74-0 ufa woyera
| Nambala ya Catalog | XD90361 |
| Dzina lazogulitsa | Streptomycin sulphate |
| CAS | 3810-74-0 |
| Molecular Formula | (C21H39N7O12)2·3H2SO4 |
| Kulemera kwa Maselo | 1457.39 |
| Zambiri Zosungira | 2 mpaka 8 ° C |
| Harmonize Tariff Code | 29412080 |
Mafotokozedwe a Zamalonda
| Gulu | USP36/EP8.0 |
| pH | 4.5-7.0 |
| Kutaya pa Kuyanika | ≤7.0% |
| Kuyesa | ≥720IU/MG |
| Sulfate | 18.0-21.5% |
| Maonekedwe | ufa woyera kapena pafupifupi woyera, wosungunuka kwambiri m'madzi, pafupifupi wosasungunuka mu Mowa. |
| Methanol | ≥0.3% |
| Streptomycin B | ≤3.0% |
| Mayeso a Colorimetric | ≥90.0% |
| Sufuric Acid | ≤1.0% |
| Kukhazikika kwa sodium sulphite | ≤0.4% |
Ngakhale kuti etiology ya intervertebral disc degeneration sichidziwika bwino, njira imodzi yopewera njirayi ingakhale yoletsa apoptosis.Pakafukufuku wapano, zotsatira za anti-apoptotic za carboxymethylated chitosan (CMCS) m'maselo a nucleus pulposus (NP) adafufuzidwa ndi cholinga chothandizira kupulumuka kwa ma disc.Makoswe NP maselo anali olekanitsidwa ndi kutukuka mu m'galasi, ndi hydrogen peroxide (H2O2) ntchito kumanga NP cell apoptosis chitsanzo.Kutheka kwa ma cell kunayesedwa ndi kuyesa kwa ma cell -8.Chiŵerengero cha ma cell a apoptotic chinawunikidwa ndi annexin V-fluorescein isothiocyanate (FITC) ndi propidium iodide (PI) kusanthula kawiri madontho, ndipo morphology idawonedwa ndi Hoechst 33342 staining.Mphamvu ya nembanemba ya mitochondrial ya ma cell a NP idawunikidwa ndi rhodamine 123 fluorescence staining.Reverse transcription (RT) ‑quantitative polymerase chain reaction (qPCR) idachitidwa kuti ayeze milingo ya mRNA ya inducible nitric oxide synthase (iNOS), caspase-3, B-cell lymphoma (Bcl)‑2, mtundu wa II collagen ndi aggrecan.Kusanthula kwa Western blot kunachitika kuti azindikire kuchuluka kwa mapuloteni a iNOS ndi Bcl-2.Zotsatira zodetsa za annexin V-FITC/PI ndi Hoechst 33342 zimasonyeza kuti CMCS inatha kuteteza maselo a NP ku apoptosis m'njira yodalira mlingo.Kudetsa kwa Rhodamine 123 kunamveketsa bwino kuti CMCS idachepetsa kuwonongeka kwa nembanemba ya mitochondrial m'maselo a NP opangidwa ndi H2O2.Kuchepa kwa caspase-3 ndi kuchuluka kwa Bcl-2 zochitika zidapezeka m'maselo a NP opangidwa ndi CMCS ndi RT-qPCR komanso kusanthula kwa blot chakumadzulo.CMCS idalimbikitsanso kufalikira ndi kutulutsa kwa mtundu wa II collagen ndi aggrecan m'maselo a NP opangidwa ndi H2O2.CMCS inasonyezedwa kuti ndi yothandiza poletsa apoptotic cell death in vitro, kusonyeza ubwino wa njira yochiritsirayi pakuwongolera kuwonongeka kwa disc.
