Spectinomycin dihydrochloride pentahydrate CAS: 22189-32-8 White crystaline ufa
Nambala ya Catalog | XD90369 |
Dzina lazogulitsa | Spectinomycin dihydrochloride pentahydrate |
CAS | 22189-32-8 |
Molecular Formula | C14H24N2O7·2HCl·5H2O |
Kulemera kwa Maselo | 495.30 |
Zambiri Zosungira | 2 mpaka 8 ° C |
Harmonize Tariff Code | 29419090 |
Mafotokozedwe a Zamalonda
Kuyesa | 99% |
Maonekedwe | White crystaline ufa |
Kufufuza za epidemiology ya molecular of isolates a Neisseria gonorrhoeae ochokera ku Saskatchewan, Canada, pogwiritsa ntchito Neisseria gonorrhoeae multi antigen sequence typing (NG-MAST), ndikuwunika mayanjano pakati pa antimicrobial susceptibility (AMS) ndi mitundu ina yamavuto (STs). , zosonkhanitsidwa pakati pa 2003 ndi 2008, zidasindikizidwa ndi NG-MAST.STs adayikidwa m'magulu ngati imodzi mwa ma alleles awo inali yofala ndipo ina imasiyana ndi ≤1% mu ndondomeko ya DNA.AMS idatsimikiziridwa ndi agar dilution (CLSI) ku maantibayotiki asanu ndi awiri.N gonorrhoeae isolate idathetsedwa kukhala 82 payekha NG-MAST STs ndi 18 NG-MAST ST magulu okhala ndi magulu 25, 3655, 921, 3654, 3657 ndi 3656 okhala ndi 53.4% (13.4%) / 320) mwa iwo okha.N gonorrhoeae zodzipatula zomwe zitha kutengeka ndi ma antimicrobial onse oyesedwa anali kwambiri (p<0.05) okhudzana ndi ST 25 (87%).Mayanjano ena ofunikira pakati pa ST ndi AMS adaphatikizapo: ST 3654 ndikudzipatula ndi zochepa zoletsa zoletsa za ≥0.03 mg / L mpaka m'badwo wachitatu wa ceph alosporins;ST 3711 (100%) ndi TRNG;ndi ST/gulu 3654 (43%) ndi chromosomal kukana penicillin ndi tetracycline.Ma ST / magulu angapo a NG-MAST adalumikizidwa kwambiri ndi zodzipatula ndi chromosomal kukana kwa tetracycline.Zodzipatula zosamva ciprofloxacin (n=5) ndi azithromycin (n=2) zimawonekera ngati ma STD.Mayanjano ofunikira adawonedwa pakati pa STs payekha, kugonana ndi zaka za wodwalayo, komanso kugawa kwachigawo ndi kwakanthawi.Kugwirizana pakati pa N gonorrhoeae AMS ndi NG-MAST STs kunadziwika ndipo kungakhale kothandiza pakulosera kwa AMS m'madera.Chifukwa ma STs m'maiko osiyanasiyana amasiyana mosiyanasiyana, kugwiritsa ntchito NG-MAST pakulosera kwa AMS padziko lonse lapansi kumafuna kuphunzira kwina.