Zogulitsa

(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine ndi chiral compound ndi ntchito zosiyanasiyana m'munda wa mankhwala.Mmodzi wofunika kugwiritsa ntchito (S)-(-) -N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine ali mu chitukuko cha selective serotonin reuptake inhibitors (SSRIs).SSRIs ndi gulu la mankhwala omwe amagwiritsidwa ntchito pochiza kuvutika maganizo, nkhawa, ndi matenda ena a maganizo.Kapangidwe kameneka kamakhala ngati kalambulabwalo kapena zinthu zoyambira pakuphatikizika kwa ma serotonin reuptake inhibitors, zomwe zimapangitsa kuti pakhale ma enantiomers omwe ali ndi mphamvu zochiritsira zowonjezera.Pophatikiza (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine mu kapangidwe ka mankhwalawa, ofufuza amatha kusintha mawonekedwe ake amankhwala, monga kuyanjana kwake ndi onyamula serotonin, kumapangitsa kuti ntchito ikhale yabwino komanso kuchepetsa zotsatira zake.Kuonjezera apo, (S) - (-) -N, N-Dimethyl-3-hydroxy-3- (2-thienyl) propanamine ingagwiritsidwe ntchito ngati chomangira popanga bioactive zina. mankhwala.Kapangidwe kake ka chiral komanso kusinthasintha kwake kumapangitsa kukhala chinthu chofunikira poyambira popanga mamolekyu ovuta.Ofufuza amatha kugwira ntchito pamasamba osiyanasiyana pa molekyulu kuti awonetse magulu osiyanasiyana kapena kusintha stereochemistry yake kuti apange anthu omwe akufuna kukhala ndi mankhwala osokoneza bongo. adaphunziridwa kuti agwiritse ntchito pochiza matenda a Parkinson.Kafukufuku wasonyeza kuti chigawochi chimasonyeza ntchito ya dopamine agonist, kutanthauza kuti ikhoza kulimbikitsa ma dopamine receptors, omwe nthawi zambiri amakhudzidwa ndi matenda a Parkinson.Ikhoza kukhala ndi mphamvu zochiritsira zochepetsera zizindikiro zokhudzana ndi matenda a neurodegenerative.Ndikofunikira kudziwa kuti (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine ndi wamphamvu. zosakanikirana, ndipo kugwiritsidwa ntchito kwake kuyenera kuchitidwa mosamala.Ofufuza ndi akatswiri omwe amagwira ntchito ndi gululi akuyenera kutsatira malangizo achitetezo ndi njira zowonetsetsa kuwongolera moyenera ndikuchepetsa zoopsa. Mwachidule, (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl propanamine ndi gawo lofunika kwambiri pakupanga ma serotonin reuptake inhibitors osankhidwa ndi mamolekyu ena a bioactive.Kapangidwe kake ka chiral, kapangidwe kake kosinthika, komanso ntchito zochizira zomwe zingachitike zimapangitsa kuti ikhale yofunikira pakufufuza zamankhwala.Kupitiriza kufufuza ndi kufufuza kwa (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine kungathandize pakupanga mankhwala atsopano komanso mankhwala omwe angakhalepo pazovuta zosiyanasiyana.