Zogulitsa

(S)-(+) -2-Chlorophenylglycine methyl ester hydrochloride ndi mankhwala okhala ndi mankhwala C9H12ClNO2·HCl.Ndi mchere wopangidwa ndi (S) - (+) -2-Chlorophenylglycine methyl ester ndi hydrochloric acid.Mankhwalawa amagwiritsidwa ntchito popanga mankhwala. Chimodzi mwazofunikira kwambiri za (S) -(+) -2-Chlorophenylglycine methyl ester hydrochloride ndi ngati chiral chomangira popanga mankhwala osiyanasiyana.Mankhwala a Chiral ndi mamolekyu omwe amapezeka mumitundu iwiri yazithunzi zagalasi, zomwe zimatchedwa enantiomers.Enantiomerically pure compounds, monga (S) -(+) -2-Chlorophenylglycine methyl ester hydrochloride, ndi ofunikira kwambiri pamakampani opanga mankhwala chifukwa amatha kuyanjana ndi zolinga zenizeni zamoyo, kuonjezera mphamvu ndi kuchepetsa zotsatira za mankhwala. wa chlorophenylglycine moiety mu (S) -(+) -2-Chlorophenylglycine methyl ester hydrochloride imapereka mwayi wopangira mankhwala osiyanasiyana.Mwachitsanzo, angagwiritsidwe ntchito ngati kalambulabwalo pa kaphatikizidwe wa nonsteroidal odana ndi kutupa mankhwala (NSAIDs), antimicrobial agents, ndi zina bioactive mankhwala.Zomwe zimayikidwa m'malo mwa chlorophenylglycine pachimake zimatha kukhala zosiyanasiyana kuti zisinthe zinthu zamoyo zomwe zimapangidwira. Komanso, (S) - (+) -2-Chlorophenylglycine methyl ester hydrochloride imatha kukhala ngati chophatikizira chapakatikati pokonzekera mamolekyu ovuta.Itha kugwiritsidwa ntchito mu multistep syntheses kuti adziwitse chirality mwa ofuna mankhwala osiyanasiyana.Mwa kuphatikiza mankhwalawa mu kaphatikizidwe, akatswiri a zamankhwala amatha kuwongolera stereochemistry ya molekyulu yomwe imachokera, kupititsa patsogolo ntchito yake yachilengedwe komanso kukhazikika kwake. ndi kusunga kophatikizana.Kuonjezera apo, mchere wa hydrochloride ukhoza kupititsa patsogolo kusungunuka kwa mankhwalawa muzitsulo zamadzimadzi, zomwe zimapangitsa kuti zikhale zosavuta kuzigwira muzochita zosiyanasiyana zopangira. ntchito mu synthesis wa mankhwala mankhwala, ntchito yake yeniyeni ndi mphamvu zingasiyane malinga ndi kufunika chandamale molekyulu ndi mmene zinthu.Pawiri ayenera kusamaliridwa mosamala, kutsatira ndondomeko yoyenera chitetezo ndi malangizo pa kaphatikizidwe ndi ntchito.