Nystatin dihydrate CAS: 1400-61-9 Nystatin A1> 85%;mankhwala ena aliwonse
Nambala ya Catalog | XD90352 |
Dzina lazogulitsa | Nystatin dihydrate |
CAS | 1400-61-9 |
Molecular Formula | Mtengo wa C47H75NO17 · 2H2O |
Kulemera kwa Maselo | 962.10 |
Zambiri Zosungira | -15 mpaka -20 ° C |
Harmonize Tariff Code | 29419000 |
Mafotokozedwe a Zamalonda
Mapeto | Zimagwirizana ndi Ph.Eur.9.7 |
Pseudomonas aeruginosa | Kulibe |
pH | 6.0-8.0 (3% yankho lamadzi) |
Kuyesa | Nystatin A1> 85%;mankhwala ena aliwonse <4% |
Kutaya pa Kuyanika | <5.0% |
Maonekedwe | ufa wachikasu kapena wofiirira |
Phulusa la Sulfated | <3.5% |
Mayeso a ID D | Zogwirizana (UV) |
Mtengo wa TAMC | <1000cfu/g |
Mtengo wa TYMC | <100cfu/g |
Staphylococcus Aureus | Kulibe |
Residual Solvent Methanol | <3000ppm |
Mesityloxide | <500ppm |
Zosungunulira Zotsalira | <5000ppm |
Mayeso a Identification (UV) A | zofanana ndi kufotokozera |
Absorbance A305 | > 0.6 |
mabakiteriya omwe ali ndi bile-tolerant gram-negative (E.coli + Salmonella sp.) | Kulibe |
Mitundu ya Clostridia | Kulibe |
Zosungunulira Zotsalira (1-butanol) | <1000ppm |
Purity;Mayeso a Microbial | NLT> 4400 IU/mg pa zouma |
Kudziwa zosintha zamankhwala kuti zisiyanitse invasive pulmonary aspergillosis (IPA) kuchokera ku colonization mwa odwala omwe ali ndi chibayo chosatha ndi chikhalidwe chabwino cha Aspergillus spp.mu zitsanzo za kupuma.Kufufuza kwamagulu obwerezabwereza kuphatikizapo odwala omwe ali ndi kupuma kwapadera kwa Aspergillus spp.mu nthawi ya zaka 10.IPA idawunikidwa molingana ndi njira za Bulpa.Zosintha zachipatala zinasonkhanitsidwa ndipo kusanthula kwazinthu zambiri kunachitika.Odwala makumi asanu ndi atatu ndi atatu omwe ali ndi kudzipatula kwa Aspergillus spp.kuchokera ku zitsanzo za kupuma zinaphatikizidwa;68.7% (n = 57) ya odwala anali ndi matenda osatha a m'mapapo, 18% (n = 15) pulmonary fibrosis ndi 13.3% (n = 11) mphumu ya bronchial.Odwala makumi awiri ndi awiri (26.6%) anali ndi IPA.Kugwiritsa ntchito fluconazole (OR 4.49; CI 95% 1.5-13.4; P = .007), kulephera kwambiri kupuma (OR 4.64; CI 95% 1.46-14.72; P = .009) ndi nthawi yogonera kuchipatala (OR 1.05; CI 95% 1.01-1.1; P = .006) adagwirizanitsidwa ndi IPA. Kugwiritsa ntchito fluconazole kusanachitike, kulephera kupuma kwakukulu komanso nthawi yogonekedwa kuchipatala kumagwirizanitsidwa ndi IPA kwa odwala omwe ali ndi chifuwa chachikulu chokhala ndi kupuma kwa Aspergillus spp.Copyright © 2012 Elsevier España, SL Ufulu Wonse zosungidwa