Neomycin Sulfate Cas: 1405-10-3
Nambala ya Catalog | XD91890 |
Dzina lazogulitsa | Neomycin sulfate |
CAS | 1405-10-3 |
Fomu ya Molecularla | Chithunzi cha C23H48N6O17S |
Kulemera kwa Maselo | 712.72 |
Zambiri Zosungira | 2-8 ° C |
Harmonize Tariff Code | 29419000 |
Mafotokozedwe a Zamalonda
Maonekedwe | White ufa |
Asay | 99% mphindi |
Malo osungunuka | >187°C (Dec.) |
alpha | D20 +54° (c = 2 mu H2O) |
refractive index | 56 ° (C=10, H2O) |
Fp | 56 ℃ |
kusungunuka | H2O: 50 mg/mL Monga njira yothetsera.Zothirira ziyenera kusungidwa pa kutentha kwa 2-8 ° C.Kukhazikika pa 37 ° C kwa masiku 5. |
PH | 5.0-7.5 (50g/l, H2O, 20℃) |
Kusungunuka kwamadzi | Zosungunuka m'madzi |
Kukhazikika | Wokhazikika.Zosagwirizana ndi ma oxidizing amphamvu. |
NEOMYCIN SULFATE ndi maantibayotiki aminoglycoside omwe amapezeka m'mankhwala ambiri apakhungu.NEOMYCIN SULFATE yagwiritsidwa ntchito ngati njira yodzitetezera ku hepatic encephalopathy ndi hypercholesterolemia.
NEOMYCIN SULFATE ndi mankhwala a aminoglycoside opangidwa ndi S. fradiae omwe amalepheretsa kumasulira kwa mapuloteni pomangirira ku gawo laling'ono la prokaryotic ribosomes.Imatchinga njira za Ca2+ zokhala ndi mphamvu zamagetsi ndipo ndi inhibitor yamphamvu ya chigoba cha minofu ya sarcoplasmic reticulum Ca2+ kumasulidwa.NEOMYCIN SULFATE yasonyezedwa kuti imalepheretsa kusintha kwa inositol phospholipid, phospholipase C, ndi phosphatidylcholine-phospholipase D ntchito (IC50 = 65 μM).Ndiwothandiza kwambiri polimbana ndi mabakiteriya a gram-positive ndi gram-negative ndipo amagwiritsidwa ntchito poletsa kuipitsidwa ndi mabakiteriya amtundu wa cell.
Neomycin sulfate ndi mankhwala opha tizilombo (angagwiritsidwe ntchito mogwira mtima motsutsana ndi mabakiteriya ambiri omwe amayambitsa matenda a khungu, maso ndi khutu lakunja);maantibayotiki ambiri mu zopaka pamutu, ufa, mafuta odzola, madontho a maso ndi makutu;systemic antibiotic ndi wolimbikitsa kukula mu ntchito ya Chowona Zanyama.