Zogulitsa

Losartan ndi mankhwala omwe ali m'gulu la mankhwala omwe amadziwika kuti angiotensin II receptor blockers (ARBs).Amagwiritsidwa ntchito makamaka pochiza kuthamanga kwa magazi (kuthamanga kwa magazi) ndi mitundu ina ya matenda a mtima.Ngati sichitsatiridwa, chingayambitse matenda aakulu monga matenda a mtima, sitiroko, ndi matenda a impso.Losartan imagwira ntchito poletsa kugwira ntchito kwa timadzi timene timatulutsa angiotensin II, yomwe imalimbitsa mitsempha yamagazi ndikupangitsa kuthamanga kwa magazi.Poletsa hormone iyi, losartan imathandiza kumasuka ndi kukulitsa mitsempha ya magazi, motero kuchepetsa kuthamanga kwa magazi.Kuphatikiza pa kuchiza matenda oopsa, losartan imapindulitsanso pazochitika zina za mtima, monga kulephera kwa mtima ndi kumanzere kwa ventricular hypertrophy.Zingathandize kusintha zizindikiro, kupititsa patsogolo ntchito ya mtima, ndi kuchepetsa chiopsezo cha zochitika za mtima kwa odwala omwe ali ndi vutoli.Kuonjezera apo, losartan yapezeka kuti ili ndi mphamvu yoteteza impso mwa anthu omwe ali ndi matenda a shuga a mtundu wa 2 ndi matenda a shuga (matenda a impso).Ikhoza kuchepetsa kuwonongeka kwa impso, kuchepetsa proteinuria (mapuloteni ochuluka mumkodzo), ndikuthandizira kusunga impso kugwira ntchito mwa anthuwa. Mlingo ndi kugwiritsa ntchito kwa losartan kumatha kusiyanasiyana malinga ndi momwe munthu alili, zaka zake, ndi zina.Amatengedwa pakamwa kamodzi patsiku, kapena popanda chakudya.Ndikofunikira kutsatira mlingo woperekedwa ndi malangizo operekedwa ndi katswiri wa zaumoyo.Monga mankhwala aliwonse, losartan ikhoza kukhala ndi zotsatirapo zake.Zotsatira zofala zingaphatikizepo chizungulire, kutopa, kupweteka mutu, ndi kukhumudwa m'mimba.Mwachidule, losartan ndi angiotensin II receptor blocker yomwe imagwiritsidwa ntchito pochiza matenda oopsa, matenda a mtima monga kulephera kwa mtima, ndi matenda a shuga.Poletsa zochita za angiotensin II, losartan imathandizira kupumula ndikukulitsa mitsempha yamagazi, potero imachepetsa kuthamanga kwa magazi ndikuwongolera magwiridwe antchito amtima.Ndi mankhwala ofunikira pakuwongolera zikhalidwezi ndipo ayenera kumwedwa monga momwe adalangizira akatswiri azaumoyo.