L-Cystine CAS: 56-89-3 99% Makristasi oyera kapena ufa wa crystalline
Nambala ya Catalog | XD90322 |
Dzina lazogulitsa | L-cystine |
CAS | 56-89-3 |
Molecular Formula | Chithunzi cha C6H12N2O4S2 |
Kulemera kwa Maselo | 240.30 |
Zambiri Zosungira | Wozungulira |
Harmonize Tariff Code | 29309013 |
Mafotokozedwe a Zamalonda
Maonekedwe | Makristasi oyera kapena ufa wa crystalline |
Kuyesa | 99% |
Gulu | Chithunzi cha USP32 |
Kuzungulira kwachindunji | -215 ° mpaka -225 ° |
Zitsulo zolemera | <0.0015% |
AS | 1.5 ppm pa |
SO4 | 0.040% kuchuluka |
Fe | <0.003% |
Kutaya pa Kuyanika | 0.20% kuchuluka |
Zotsalira pa Ignition | 0.10% kuchuluka |
Cl | 0.10% kuchuluka |
Makristalo a carboxypeptidase T (CpT) okhala ndi phenylalanine ndi arginine substrate analogi - benzylsuccinic acid ndi (2-guanidinoethylmercapto) succinic acid - adatsimikiziridwa ndi njira yosinthira mamolekyulu pazosankha za 1.57 Å ndi 1.62 mbiri yotakata Å wa enzyme.Zotsalira za Leu211 ndi Leu254 zotsalira (zopezekanso mu carboxypeptidase A ndi carboxypeptidase B) zidawonetsedwa kuti ndizodziwikiratu ma hydrophobic substrates, pomwe Asp263 inali yozindikiritsa magawo okhala ndi charger.Kusintha kwa zinthuzi kumasintha mbiri ya gawo lapansi: mtundu wa CpT Leu211Gln umapeza zinthu ngati carboxypeptidase B, ndi mtundu wa CpT wa Asp263Asn kusankha kwa carboxypeptidase A.Lupu ya Pro248-Asp258 yolumikizana ndi Leu254 ndi Tyr255 idawonetsedwa kuti ili ndi udindo wozindikira zotsalira za C-terminal.Kumanga kwa gawo laling'ono pagawo la S1' kumabweretsa kusintha kwa ligand-dep kwa loop, ndipo Leu254 side chain movement imapangitsa kukonzanso kotsalira kwa Glu277 kofunika kwambiri pakuthandizira.Ichi ndi chidziwitso chatsopano cha kusankha kwa gawo lapansi kwa metallocarboxypeptidase komwe kukuwonetsa kufunikira kwa kuyanjana pakati pa malo a S1' ndi catalytic center.