D-Valine Cas: 640-68-6 C5H11NO2
Nambala ya Catalog | XD90291 |
Dzina lazogulitsa | D-Valine |
CAS | 640-68-6 |
Molecular Formula | C5H11NO2 |
Kulemera kwa Maselo | 117.14634 |
Zambiri Zosungira | Chipinda Temp |
Harmonize Tariff Code | 29224995 |
Mafotokozedwe a Zamalonda
Kuyesa | 99% |
Maonekedwe | White ufa |
Kuchulukana | 1.2000 (chiyerekezo) |
Malo osungunuka | >295 °C (pansi.) |
Malo otentha | 213.6 °C pa 760 mmHg |
pophulikira | 83 ℃ |
Refractive index | -27 ° (C=8, 6mol/L HCl) |
Kusungunuka | 56 g/L (20°C) |
Kusungunuka kwamadzi | 56 g/L (20 ºC) |
PSA | 63.32000 |
LogP | 0.75460 |
Kuzungulira kwachindunji | -27.5 º (c=5, 5N HCl) |
Optical ntchito | [α]23/D −32.0 mpaka −24.0°, c = 8 mu 6 M HCl |
Azimayi omwe ali ndi matenda a antiphospholipid (APS) ali pa chiopsezo chowonjezereka cha kutaya mimba mobwerezabwereza (RPL) ndi preeclampsia.Antiphospholipid antibodies (aPL) amasintha mwachindunji ntchito ya trophoblast.Chithandizo chochepa cha molecular weight heparin (LMWH) chimachepetsa chiopsezo cha RPL koma osati preeclampsia.Komanso, LMWH imalimbikitsa trophoblast sFlt-1 kumasulidwa, anti-angiogenic factor yokhudzana ndi preeclampsia.Popeza kusowa kwa vitamini D kumayenderana ndi APS ndi preeclampsia, kafukufukuyu adafuna kudziwa momwe vitamini D imagwirira ntchito pa trophoblast ntchito pokhazikitsa aPL ndi LMWH. opanda aPL pamaso ndi kusowa kwa vitamini D, LMWH kapena zonse ziwiri.Trophoblast secretion of inflammatory cytokines ndi angiogenic factor inayesedwa ndi ELISA.Vitamini D yokha kapena kuphatikiza ndi LMWH inalepheretsa kuyankha kwa kutupa kwa aPL-induced trophoblast m'maselo a HTR8 ndi zikhalidwe zoyambirira.Ngakhale kuti vitamini D sanakhudzidwe ndi aPL-mediated modulation of angiogenic factor in the primary trophoblast, inaletsa kwambiri LMWH-induced sFlt-1 kumasulidwa.LMWH pamodzi ndi vitamini D kungakhale kopindulitsa kuposa chithandizo chamankhwala amodzi mwa kuteteza aPL. -kupangitsa kutupa kwa trophoblast ndikubwezeretsa kutulutsa kwa LMWH-induced sFlt-1.