5-Iodo-2'-deoxycytidine CAS: 54-42-2 98-102% ufa woyera wa crystalline
| Nambala ya Catalog | XD90562 |
| Dzina lazogulitsa | 5-Iodo-2'-deoxycytidine |
| CAS | 54-42-2 |
| Molecular Formula | C9H11IN2O5 |
| Kulemera kwa Maselo | 354.10 |
| Zambiri Zosungira | 2 mpaka 8 ° C |
| Harmonize Tariff Code | 29349990 |
Mafotokozedwe a Zamalonda
| Maonekedwe | White crystalline ufa |
| Kuyesa | 99% |
| Kuzungulira kwachindunji | +25 mpaka +30 |
| Zitsulo zolemera | <0.001% |
| Kutaya pa Kuyanika | <1.0% |
| Zotsalira pa Ignition | <0.3% |
Kapangidwe kodziwikiratu ka 3D ka DNA yazingwe ziwiri imapangitsa kuti ikhale yoyenera ngati template yopangira mawebusayiti opangidwa ndi nucleic acid.Pano tikuwunika kagwiritsidwe ntchito ka 14mer DNA duplex ngati scaffold kuti tidziwike bwino komanso modziwikiratu za magwiridwe antchito.Poganizira za kutenga nawo mbali kulikonse kwa histidine-based imidazole gulu mu kuzindikira mapuloteni ndi catalysis zochitika, single histidine-ngati kusinthidwa duplexes anafufuzidwa.Kuyika histamine ku C5 ya maziko a thymine kudzera pa chomangira cha amide, kumalola kusinthasintha kwa ntchito ya imidazole mu poyambira chachikulu.Kugwirizana pakati pa imidazole ndi duplex ndi mphamvu yake pa imidazolium pKaH amafufuzidwa poika thymine imodzi yosinthidwa pa malo anayi osiyana pakati pa 14mer double helix.Pogwiritsa ntchito NMR ndi mphamvu zopanda malire za ma molekyulu, ndondomeko yowonongeka yomwe imaphatikizapo kupanga mgwirizano wa haidrojeni pakati pa imidazole ndi Hoogste kumbali ya guanine yamagulu awiri oyandikana nawo a GC amakhazikitsidwa.Cholingacho chimathandizira kukhazikika kwa kutentha kwa 6 ° C ndipo ndizofunikira pakusintha pKaH ya gulu la imidazolium.Zomwe zimapangidwira, zofunikira komanso mawonekedwe amtundu watsopano wa pKaH-regulating motif akufotokozedwa.
