Zogulitsa

4''-Propyl-3-fluorobiphenyl-4-boronic acid, yomwe imadziwikanso kuti (4-propyl-3-fluorophenyl) boroni acid, ndi mankhwala omwe agwiritsidwa ntchito kwambiri m'madera osiyanasiyana, kuphatikizapo organic synthesis, science science, ndi kafukufuku wamankhwala.Mmodzi mwa ntchito zoyambira za 4''-Propyl-3-fluorobiphenyl-4-boronic acid ndikusintha machitidwe olumikizana azitsulo.Gululi limatha kukhala ngati chomangira cha boronic acid, chomwe chimalola kupanga ma bondi a carbon-carbon kapena carbon-heteroatom.Mwachitsanzo, angagwiritsidwe ntchito mu Suzuki-Miyaura cross-coupling reactions, kumene amachitira ndi aryl kapena vinyl halides pansi pa palladium catalysis kuti apange biaryl mankhwala.Kuphatikizika kumeneku kumagwiritsidwa ntchito kwambiri popanga mamolekyu ovuta, kuphatikiza mankhwala, agrochemicals, ndi zida. amapereka mwayi wapadera kwa chitukuko cha zipangizo zinchito.Kulowetsedwa kwa fluorine kumatha kukhudza kwambiri mawonekedwe a physicochemical a molekyulu, monga kugawa kwake pamagetsi ndi hydrophobicity.Zinthu izi zimapanga zotumphukira za 4''-Propyl-3-fluorobiphenyl-4-boronic acid zothandiza pazantchito zosiyanasiyana, monga makhiristo amadzimadzi, OLED (organic light-emitting diode), ndi zida zina zamagetsi. Kuphatikiza apo, gulu la propyl mu kapangidwe ka 4''-Propyl-3-fluorobiphenyl-4-boronic acid amalola kuti atulutsidwe mosavuta, kupereka mwayi wopeza zinthu zambiri zotumphukira.Kusinthasintha kumeneku kumathandizira kaphatikizidwe wamitundu yosiyanasiyana yokhala ndi zida komanso magwiridwe antchito.Zotengera izi zitha kusinthidwanso kapena kuphatikizidwa muzinthu zazikulu zamamolekyulu kuti apange zovuta za organic, mamolekyu a bioactive, ndi zida zapamwamba. omwe angakhale ofuna kupeza mankhwala.Mafuta opangidwa ndi fluorinated nthawi zambiri amawonetsa kukhazikika kwa metabolic, kuchuluka kwa lipophilicity, ndi kusintha kwachilengedwe kwachilengedwe poyerekeza ndi anzawo omwe alibe fluorinated.Chifukwa chake, kuyambitsidwa kwa atomu ya fluorine mu mamolekyu omwe amagwira ntchito mwachilengedwe kumatha kupititsa patsogolo mphamvu zawo zamankhwala, monga potency ndi kusankha. , sayansi ya zinthu, ndi kafukufuku wamankhwala.Kuthekera kwake kutenga nawo gawo pakusintha kwazitsulo zolumikizidwa ndi zitsulo, zinthu zapadera zomwe zimagwirizanitsidwa ndi kulowetsedwa kwa fluorine, komanso kuthekera kotulutsa kumapangitsa kukhala chida chamtengo wapatali chopangira mamolekyu ovuta, zida zogwirira ntchito, komanso omwe angakhale ofuna mankhwala.