Zogulitsa

4-Hydroxyphenylboronic acid pinacol ester, yomwe imadziwikanso kuti HBP ester, ndi mankhwala omwe amapeza ntchito m'madera osiyanasiyana chifukwa cha zinthu zake zapadera monga boronic ester.Kapangidwe kake kake kamakhala ndi atomu ya boron yolumikizidwa ndi gulu la phenolic kudzera pa kulumikizana kwa ester, ndikupangitsa kuti ikhale yomangamanga yomangira organic synthesis.Mu organic synthesis, 4-Hydroxyphenylboronic acid pinacol ester imagwiritsidwa ntchito ngati reagent pamtanda wa Suzuki-Miyaura. - kugwirizana anachita.Izi zimaphatikizapo kupanga mgwirizano wa carbon-carbon pakati pa aryl kapena vinyl boronic acid ndi aryl kapena vinyl halide kapena triflate.Monga ester ya boronic, HBP ester imakhala ngati kalambulabwalo wa asidi a boronic, omwe amatha kugwirizanitsa ndi ma electrophiles osiyanasiyana, zomwe zimapangitsa kuti pakhale ma molecule ovuta.Izi zimagwira ntchito kwambiri mu chemistry yamankhwala, kaphatikizidwe ka agrochemical, sayansi yazinthu, ndi madera ena ambiri a organic synthesis. molekyu.Mwachitsanzo, gulu la hydroxyl la phenolic moiety likhoza kutetezedwa ndipo kenako kutetezedwa, kulola kusinthidwa kosankhidwa ndi kusiyanasiyana kwa pawiri.Katunduyu amachititsa HBP ester kukhala chida chamtengo wapatali pakupanga mankhwala, agrochemicals, ndi mankhwala ena abwino.Chifukwa cha atomu ya boron m'mapangidwe ake, imatha kupanga zovuta zosinthika ndi ma diol kapena ma polyols, monga shuga kapena chakudya.Katunduyu amathandizira kupanga masensa opangidwa ndi boronate kuti azindikire shuga, komanso mamolekyu ena okhudzana ndi biologically.HBP ester ikhoza kuphatikizidwa m'magulu osiyanasiyana ozindikira, kuphatikizapo fluorescent kapena colorimetric probes, kupereka njira yodziwira zowunikira zenizeni mu zitsanzo zamoyo kapena zachilengedwe.Kupatulapo ntchito yake mu organic synthesis ndi sensing applications, 4-Hydroxyphenylboronic acid pinacol ester yafufuzidwanso. chifukwa cha ntchito yake yomwe ingatheke mu machitidwe operekera mankhwala.Atomu ya boron imatha kutenga nawo mbali poyanjana ndi ma biomolecules, monga ma nucleic acid kapena mapuloteni, ndipo yafufuzidwa kuti ipereke mankhwala osokoneza bongo, kuwonjezereka kwa ma cell, kapena kutulutsidwa kwa mankhwala ochizira. amagwiritsidwa ntchito mu organic synthesis, sensing application, ndi machitidwe operekera mankhwala.Magwiridwe ake a boronic ester amamuthandiza kuti atenge nawo mbali pakuchitapo kanthu kwa Suzuki-Miyaura ndikusinthika kwamagulu, ndikukulitsa ntchito yake yopanga.Kuphatikiza apo, HBP ester imatha kupanga ma complex osinthika okhala ndi ma diol, kuwapangitsa kukhala ofunikira pakupanga masensa a ma cell.Kuthekera kwake munjira zoperekera mankhwala kumatsimikiziranso kufunikira kwake monga gulu losunthika m'magawo osiyanasiyana asayansi ndiukadaulo.