Zogulitsa

4-Chlorophenylboronic acid ndi organic pawiri kuti amapeza ntchito yaikulu m'madera osiyanasiyana, kuphatikizapo organic synthesis, mankhwala umagwirira, ndi zipangizo sayansi.Amakhala ndi mphete ya phenyl yomwe imalowetsedwa ndi gulu la chloro (-Cl) ndi gulu la boronic acid (-B (OH) 2) . Imodzi mwa ntchito zazikulu za 4-Chlorophenylboronic acid ndi ntchito yake monga reagent yamtengo wapatali mu palladium-catalyzed. machitidwe ophatikizana, monga Suzuki-Miyaura ndi Heck reactions.Zochita izi zimaphatikizapo kupanga ma bond a carbon-carbon, pomwe 4-Chlorophenylboronic acid imakhala ngati gwero la boron lomwe lingagwirizane ndi ma electrophiles osiyanasiyana, monga aryl kapena vinyl halides.Izi zimathandiza kuphatikizika kwa mitundu yosiyanasiyana yamagulu achilengedwe, kuphatikiza mankhwala, agrochemicals, ndi zinthu.Mwachitsanzo, imatha kukhala ndi ma amination reaction kuti ipange 4-chloro-phenylboronates, yomwe imatha kukhala yothandiza pakupanga mitundu yosiyanasiyana yokhala ndi nayitrogeni.Kusiyanasiyana kwa gululi kumapangitsa kuti 4-Chlorophenylboronic acid ipangidwe, zomwe zimapangitsa kuti pakhale mamolekyu ovuta omwe ali ndi katundu wopangidwa.Zawonetsa lonjezo ngati pharmacophore kapena chomangira chopangira ma bioactive mankhwala.Chifukwa cha kuchuluka kwa boronate, 4-Chlorophenylboronic acid imatha kupanga zomangira zosinthika zosinthika ndi ma molekyulu okhala ndi diol, monga ma carbohydrate ndi ma nucleotides.Kulumikizana uku kwagwiritsidwa ntchito popanga ma enzyme inhibitors, receptor ligands, ndi mankhwala ena.Mwachitsanzo, boronic acid-based proteasome inhibitors apangidwa kuti athe kuchiza angapo myeloma.Mu gawo la sayansi yazinthu, 4-Chlorophenylboronic acid yapeza ntchito pakusintha kwamalo kapena kaphatikizidwe kazinthu zogwirira ntchito.Pogwiritsa ntchito gulu la boronic acid, imatha kupanga zolimba zosinthika zokhala ndi ma polyols kapena okhala ndi hydroxyl.Katunduyu atha kugwiritsidwa ntchito kuti agwire ntchito pamtunda, monga kupanga zokutira zomwe zimakhudzidwa ndi zomwe zimakhudzidwa kapena kukonza zowunikira kuti zizindikire ma carbohydrate kapena ma analyte ena. , ndi sayansi ya zinthu.Kukhazikikanso kwake mu mapangidwe a carbon-carbon bond, kuthekera kwa kuyambitsa gulu logwira ntchito, komanso kuthekera kopanga ma covalent bond osinthika kumapangitsa kukhala chida chofunikira kwa ofufuza m'magawo osiyanasiyana asayansi.