4-Amino-1-((2R,4S,5R) -4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-imodzi Cas:951-77-9
Nambala ya Catalog: | XD90580 |
Cas: | 951-77-9 |
Molecular formula: | Chithunzi cha C9H13N3O4 |
Kulemera kwa Molecular: | 227.22 |
kupezeka: | Zilipo |
Mtengo: | |
Kupakiratu: | 1g USD10 |
Paketi Yambiri: | Pemphani Quote |
Mafotokozedwe a Zamalonda
Maonekedwe | White crystalline ufa |
Kuyesa | 99% |
Melting Point | 196 ° C - 200 ° C |
Thymidine phosphorylase (TP, EC 2.4.2.4) adazindikira mawonekedwe a gawo lapansi ndi mawonekedwe apamwamba, kudzera m'munsi ndi ma ribosyl moieties.Kulowetsedwa kwa 3'-OH ya thymidine kunakhudza kwambiri ntchito yake yothandizira ndi TP.Kutembenuka kwa ma nucleosides a pyrimidine okhala ndi zigawo zosinthidwa kukhala mawonekedwe a 1-phosphate kunali koyipa.Zochita za gulu lochoka zidachepa ndikuwonjezeka kwa kununkhira kwa pyrimidine base moiety, chifukwa chazovuta pakuyika maziko ndi ma amino acid omwe amakhala komweko.Kusintha kwa magulu a 3' ndi 5' kumachepetsa kuchuluka kwa zomwe zimachitika komanso kutembenuka kwa TP.Makamaka gulu la ribosyl 3' hydroxyl linali lofunika kwambiri pomanga gawo lapansi ndi enzyme.The kinetic assay anasonyeza bwino K(m) mkulu ndi V (max) otsika mtengo m'malo 3' hydroxyl gulu ndi haidrojeni.