Zogulitsa

3-Tolylboronic acid, yomwe imadziwikanso kuti 3-methylphenylboronic acid, ndi mankhwala omwe amagwiritsidwa ntchito kwambiri popanga organic synthesis ndi chemistry yamankhwala. Chimodzi mwazofunikira kwambiri za 3-Tolylboronic acid ndikugwiritsa ntchito kwake posintha zitsulo zolumikizana ndi zitsulo. .Gululi limagwira ntchito ngati chomangira cha boronic acid, chomwe chimathandiza kupanga ma bondi a carbon-carbon kapena carbon-heteroatom.Mwachitsanzo, imatha kutenga nawo gawo muzolumikizana za Suzuki-Miyaura, pomwe imakumana ndi aryl kapena vinyl halide pansi pa palladium catalysis kuti ipereke mankhwala a biaryl.Kuphatikizika kotereku kumakhala ndi zofunikira zambiri pakupanga ma molecule ovuta, kuphatikiza mankhwala, agrochemicals, ndi zinthu zina zamtengo wapatali.Cholowa m'malochi chikhoza kukhudza kuyambiranso kwapawiri, kusankha, ndi zochitika zamoyo.Kuphatikiza apo, itha kukhala ngati gulu loteteza magulu ena ogwira ntchito panthawi yakusintha kopanga.Zinthu izi zimapangitsa 3-Tolylboronic acid kukhala chipika chomangira chomangira chamitundu yosiyanasiyana ya mamolekyulu. Mu chemistry yamankhwala, 3-Tolylboronic acid ndi zotuluka zake ndizosangalatsa ngati ofuna kumwa mankhwala.Kukhalapo kwa gulu la methyl kumatha kusinthira kuyanjana kwapawiri ndi zolinga zachilengedwe, kukhudza mphamvu yake komanso kusankha kwake.Kuphatikiza apo, boronic acid moiety imatha kupanga zomangira zosinthika zosinthika ndi ma enzymes ena, kupereka njira zopangira ma enzyme inhibitors.Kugwiritsiridwa ntchito kwake mu kusintha kwapangidwe kumapangitsa kuti pakhale chitukuko cha mamolekyu ambiri omwe ali ndi mankhwala omwe ali ndi katundu wopangidwa.Ikhoza kuphatikizidwa muzinthu zapamwamba, kuphatikizapo ma polima ndi zitsulo-organic frameworks, kuti adziwe ntchito zenizeni.Pawiriyi imathanso kukhala ngati ligand pakusintha zitsulo, kupangitsa kuti azitha kuchita zinthu zothandiza komanso kusankha bwino pamachitidwe osiyanasiyana, monga hydrogenation ndi oxidation. zinthu sayansi, ndi catalysis.Ntchito yake ngati boronic acid yomanga chipika imalola kupanga mapangidwe ovuta a kaboni, kuwapangitsa kukhala ofunikira pakuphatikizika kwazinthu zogwira ntchito za biologically.Kuphatikiza apo, kukhalapo kwa gulu la methyl kumapereka mwayi wosintha zinthu zomwe zimachokera, ndipo kugwiritsidwa ntchito kwake muzinthu ndi catalysis kumakulitsa magwiridwe antchito azinthu zapamwamba komanso kukhudza kusintha kwamankhwala.