Zogulitsa

3-Fluoro-4'-propyl-biphenylboronic acid ndi mankhwala omwe ali m'gulu la boronic acid.Amakhala ndi mphete ya biphenyl yokhala ndi gulu la propyl lomwe limamangiriridwa kumapeto ndi atomu ya fluorine yomwe imayikidwa kumapeto kwina, komanso gulu la boronic acid.Pawiri Izi ali angapo ntchito m'minda ya organic kaphatikizidwe, umagwirira mankhwala, ndi zipangizo sayansi.Mmodzi wa ntchito yaikulu ya 3-Fluoro-4'-propyl-biphenylboronic asidi ndi monga lumikiza reagent mu kaphatikizidwe organic.Amagwiritsidwa ntchito kwambiri mu Suzuki-Miyaura cross-coupling reactions, zomwe ndi njira zamphamvu zopangira ma carbon-carbon bond.Kapangidwe kameneka kamakhala ngati boronate ester, kuchitapo kanthu ndi aryl kapena vinyl halides pansi pa palladium catalysis kuti apange mankhwala a biaryl kapena styryl.Kukhalapo kwa atomu ya fluorine ndi gulu la propyl mu kapangidwe kameneka kumatha kukhudza reactivity ndi selectivity wa cross-coupling reaction, ndikupangitsa kukhala chosunthika chomangira cha kaphatikizidwe ka mamolekyu ovuta a organic. -4'-propyl-biphenylboronic asidi angagwiritsidwe ntchito pakupanga ndi kaphatikizidwe wa biologically yogwira mankhwala.Kukhalapo kwa gulu la boronic acid kumapangitsa kuti pakhale mgwirizano wosinthika wa covalent ndi ma biomolecules, monga ma enzymes kapena mapuloteni olandirira.Mankhwalawa amadziwika kuti boronate-based inhibitors ndipo amatha kugwiritsidwa ntchito poyang'ana ma enzyme omwe amakhudzidwa ndi matenda monga khansa kapena shuga.Atomu ya fluorine ndi gulu la propyl lingathandizenso kukonzanso mankhwala a mankhwala a mankhwalawa, monga potency, selectivity, ndi metabolic stability.Kuonjezera apo, 3-Fluoro-4'-propyl-biphenylboronic acid ili ndi ntchito zomwe zingatheke mu sayansi yazinthu.Ma asidi a boronic amadziwika chifukwa cha kuthekera kwawo kuchitapo kanthu ndi ma diol kapena ma polyols, kupanga zomangira zolimba.Katunduyu atha kugwiritsidwa ntchito m'munda wa sayansi ya polima kuti apange zida zodzichiritsa zokha kapena misonkhano ya supramolecular.Pogwiritsa ntchito mankhwalawa mu ma polima kapena zokutira, ochita kafukufuku amatha kuwonetsa ntchito ya boronic acid, yomwe imalola kuti maubwenzi osinthika komanso athe kukonzanso zowonongeka kapena kubwezeretsanso makina. ndikugwiritsa ntchito mu organic synthesis, chemistry yamankhwala, ndi sayansi yazinthu.Magulu ake a reactivity ndi apadera ogwira ntchito amapereka mwayi wopanga ma carbon-carbon bonds muzogwirizanitsa zogwirizanitsa, mapangidwe ndi kaphatikizidwe ka mankhwala a biologically yogwira ntchito, ndi kupanga zida zosinthika.Magulu a fluorine ndi propyl amathandizira kuti pawiri pawonjezeke ndikuwongolera mphamvu zake zamankhwala kapena zakuthupi.Izi zimapangitsa 3-Fluoro-4'-propyl-biphenylboronic acid kukhala chida chofunikira kwa asayansi ndi ofufuza m'mafakitale osiyanasiyana, zomwe zimathandizira kupita patsogolo kwakupeza mankhwala, uinjiniya wazinthu, ndi magawo ena okhudzana nawo.