2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-imodzi Cas:1044871-04-6
Nambala ya Catalog | XD90961 |
Dzina lazogulitsa | 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-chimodzi |
CAS | 1044871-04-6 |
Molecular Formula | C24H29N3O4 |
Kulemera kwa Maselo | 423.5 |
Zambiri Zosungira | |
Harmonize Tariff Code |
Mafotokozedwe a Zamalonda
Maonekedwe | |
Kuyesa | |
Bmalo opangira mafuta | 612.6±65.0 °C(Zonenedweratu) |
Kuchulukana | 1.25±0.1 g/cm3(Zonenedweratu) |
Acidity coefficient | (pKa)9.54±0.20(Zonenedweratu) |
RVX-297 ndi yamphamvu kwambiri, yogwira pakamwa BET inhibitor kusankha BD2.Ma IC50 a RVX-297 a BRD2(BD2), BRD3(BD2), ndi BRD4(BD2) anali 0.08, 0.05, ndi 0.02 μM, motsatana.RVX-297 imalepheretsa kufotokoza kwa mitundu yosiyanasiyana ya ma cell otupa.Kuchita bwino kwa RVX-297 mu zitsanzo zoyambira za kutupa kwakukulu ndi autoimmunity.
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